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Rational Pharmacotherapy in Cardiology

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Vol 13, No 3 (2017) PHARMACOGENETIC ASPECTS OF NEW ORAL ANTICOAGULANTS APPLICATION Abstract  similar documents
A. V. Kryukov, D. A. Sychev, O. V. Tereshchenko
"... polymorphism, respectively. There was no significant effect of ABCB1 gene rs2032582 and rs1045642 polymorphisms ..."
 
Vol 9, No 6 (2013) THE ROLE OF P-GLYCOPROTEIN IN RATIONAL PHARMACOTHERAPY IN CARDIOLOGY Abstract  similar documents
A. V. Shulkin, E. N. Yakusheva, N. M. Popova
"... agents and anticoagulants. Determination of C3435T polymorphism of multidrug resistance gene (MDR1 ..."
 
Vol 4, No 1 (2008) ACUTE CEREBROVASCULAR EVENTS IN PATIENTS WITH ARTERIAL HYPERTENSION: MOLECULAR GENETIC ASPECTS Abstract  similar documents
M. A. Karpenko, E. G. Shatskaya, V. N. Solntsev, M. A. Bogdanov, V. I. Larionova
"... Aim. To study association between stroke and gene polymorphism of angeotensin converting enzyme ..."
 
Vol 4, No 2 (2008) EFFECT OF GENES SLCO1B1 AND MDR1 POLYMORPHISM ON ATORVASTATIN PHARMACOKINETICS AND PHARMACODYNAMICS IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA: RESULTS OF PILOT PHARMACOGENETICS STUDY Abstract  similar documents
A. V. Semenov, D. A. Sichev, V. G. Kukes
"... Aim. To study effects of genes SLCO1B1 and MDR1 polymorphism on atorvastatin pharmacokinetics ..."
 
Vol 6, No 4 (2010) CLOPIDOGREL PHARMACOGENETICS Abstract  similar documents
A. N. Meshkov
"... of clopidogrel play an important role in the resistance development. Allel variants of the gene cytochrome CYP2C ..."
 
Vol 11, No 1 (2015) ASPECTS OF LIPID-LOWERING THERAPY WITH ATORVASTATIN IN PATIENTS WITH MYOCARDIAL INFARCTION FROM THE PERSPECTIVE OF PERSONALIZED MEDICINE Abstract  similar documents
M. V. Solodun, S. S. Yakushin
"... Aim. To analyze the impact of the SLCO1B1*5 (c.521T> C) and LIPC (C514T) genes polymorphisms ..."
 
Vol 14, No 5 (2018) Associations of Cardiovascular Risk Factors and Genetic Markers with Development of Arterial Hypertension in the Population of Mountain Shoriya Abstract  similar documents
T. A. Mulerova, S. A. Maksimov, M. Yu. Ogarkov, O. V. Gruzdeva, A. V. Ponasenko, V. N. Maksimov, M. I. Voyevoda, E. S. Filimonov, G. V. Artamonova
"... . Polymorphisms of genes  ACE (I/D, rs 4340), АGT (c.803T>C, rs699), AGTR1 (А1166С, rs5186), ADRB1 (с.145A>G, Ser ..."
 
Vol 7, No 2 (2011) PREDICTIVE ROLE OF CONNEXIN 40 IN THE PATHOGENESIS OF HEREDITARY SICK SINUS SYNDROME Abstract  similar documents
S. Yu. Nikulina, A. A. Chernova, V. A. Shulman, T. S. Kukushkina, M. I. Voevoda, V. N. Maksimov
"... for the polymorphism of 44G>A of gene Cx40. According to allele-specific polymerase chain reaction 3 types of genotypes ..."
 
Vol 15, No 3 (2019) Multi-Ethnic Analysis of Cardiac Pharmacogenetic Markers of Cytochrome P450 and Membrane Transporters Genes in the Russian Population Abstract  similar documents
K. B. Mirzaev, D. S. Fedorinov, D. V. Ivashchenko, D. A. Sychev
"... », «CYP4F2», «CYP4F1», «ABCB1», «SLCO1B1», «VKORC1», «GGCX», «SULT1A1», «CULT1», «CES1», «gene», «genes ..."
 
Vol 14, No 4 (2018) Role of Single Nucleotide Polymorphism of СУР17А Gene in the Development of Stroke Abstract  similar documents
S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, A. A. Semenchukov, O. V. Marilovceva, S. S. Tret'jakova, I. I. Lebedeva, V. N. Maksimov
"... the risk factors of this complex cascade process. Studies of gene polymorphism as a factor of genetic ..."
 
Vol 13, No 3 (2017) GENETIC ASPECTS OF MODIFIABLE RISK FACTORS ASSOCIATED WITH ARTERIAL HYPERTENSION BY THE EXAMPLE OF THE INDIGENOUS POPULATION OF MOUNTAIN SHORIYA Abstract  similar documents
T. A. Mulerova, G. V. Artamonova, M. I. Voevoda, O. V. Gruzdeva, M. Yu. Ogarkov, O. L. Barbarash
"... and instrumental examination. Polymorphisms of genes ACE (I/D, rs 4340), ADRB1 (s.145A> G, Ser49Gly, rs1801252 ..."
 
Vol 12, No 3 (2016) GENETIC PREDICTORS OF ATRIAL FIBRILLATION Abstract  PDF (Eng)  similar documents
A. V. Kuskaeva, S. Yu. Nikulina, A. A. Chernova, N. V. Aksyutina
"... genetic heart disease. In most cases, certain combinations of polymorphisms of different genes promote ..."
 
Vol 14, No 5 (2018) Pharmacogenetic and Clinical Predictors of Clopidogrel Insufficiency in a Patient with Atherosclerosis Obliterans of the Lower Extremities: Clinical Case Abstract  similar documents
M. A. Andreyanova, K. B. Mirzaev, D. A. Sychev, K. A. Ryzhikova, A. V. Pokrovsky, A. F. Kharazov
"... therapy in this patient, namely, the  carriage of polymorphic markers  of the  ABCB1 CT, CES1 CA and  CYP3 ..."
 
Vol 6, No 5 (2010) THE POLYMORPHISM OF Α2B-ADRENERGIC RECEPTOR GENE — A NEW GENETIC MARKER OF THE HEREDITARY SICK SINUS SYNDROME Abstract  similar documents
S. Iu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, M. I. Voevoda, V. N. Maksimov
"... . Genotypic examination of gene ADRA2B I/D polymorphism was performed in 213 individuals: 75 SSS-patients, 49 ..."
 
Vol 13, No 5 (2017) POLYMORPHISMS OF ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE AS PREDICTORS OF WOLFF-PARKINSON-WHITE SYNDROME Abstract  similar documents
G. V. Matyushin, S. Yu. Nikulina, A. A. Chernova, I. I. Lebedeva, A. A. Semenchukov
"... of WPW syndrome with the polymorphism of endothelial nitric synthase gene (NOS3), and to identify genetic ..."
 
Vol 12, No 5 (2016) Hypertrophic Cardiomyopathy and Connective Tissue Dysplasia Syndrome: Comorbidity Variants Abstract  similar documents
Yu. N. Belenkov, E. V. Privalova, V. Yu. Kaplunova, I. S. Chekneva, Yu. I. Najmann, M. V. Kozhevnikova, G. A. Shakaryants, A. S. Lishuta
"... patient were performed in all patients to identify comorbidities. Genotyping of polymorphisms of 12 ..."
 
Vol 6, No 3 (2010) ASSOCIATION OF CLINICAL AND GENETIC FACTORS WITH LEFT VENTRICLE HYPERTROPHY IN ARTERIAL HYPERTENSION Abstract  PDF (Eng)  similar documents
T. Yu. Kuznetsova, D. V. Gavrilov, L. M. Samohodskaya, D. V. Rebrikov, S. A. Morozova, P. I. Makarevich, A. V. Kolotvin, A. B. Balatsky, A. Yu. Postnov, S. A. Boitsov
"... of restriction fragments length polymorphism, while with substitutions of the angiotensinogen М235Т, G(-6)A gene ..."
 
Vol 12, No 5 (2016) Treatment Adherence as a New Choice Factor for Optimization of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation and Hemostatic Gene Polymorphisms Abstract  PDF (Eng)  similar documents
Yu. P. Skirdenko, A. V. Shustov, V. V. Zherebilov, N. A. Nikolayev
"... gene polymorphisms. Results. Patients receiving anticoagulation therapy are characterized by lower ..."
 
Vol 15, No 3 (2019) Study of the Association of V640L (rs6133) Polymorphism in the Platelet P-selectin Gene with Acetylsalicylic Acid Resistance in Patients after Coronary Bypass Surgery Abstract  similar documents
A. A. Kosinova, T. S. Mongush, M. D. Goncharov, T. N. Subbotina, K. S. Semashchenko, G. Y. Kochmareva, Yu. I. Grinshtein
"... Aim. To study the association of V640L (rs6133) polymorphism in the P-selectin gene ..."
 
Vol 8, No 6 (2012) GENETIC PREDICTORS OF IDIOPATHIC SICK SINUS SYNDROME Abstract  similar documents
A. A. Chernova, S. Yu. Nikulina, S. S. Tret'yakova
"... . The definition of this pathology is presented; the main symptoms are described, as well as genes that influence ..."
 
Vol 4, No 2 (2008) CLINICAL AND GENETIC PECULIARITIES OF ATRIAL FIBRILLATION Abstract  similar documents
S. Y. Nikulina, V. A. Schulman, O. O. Kuznetsova, N. V. Aksjutina, P. A. Shesternja, A. A. Chernova, V. N. Maksimov, I. V. Kulikov, S. N. Ustinov, Y. L. Kazarinova, A. G. Romashchenko, M. I. Voevoda
"... and secondary AF with gene polymorphism of β1-adrenoreceptors. Material and methods. 103 probands with AF ..."
 
Vol 7, No 4 (2011) PROTHROMBOTIC POLYMORPHISMS AND LONG-TERM PROGNOSIS OF PATIENTS WITH STABLE ISCHEMIC HEART DISEASE Abstract  similar documents
A. L. Komarov, O. O. Shahmatova, D. V. Rebrikov, D. Yu. Trophimov, T. I. Kotkina, T. A. Ilyushenko, A. D. Deev, E. P. Panchenko
"... prevalence and prognostic value of mutations and polymorphisms in genes that encode blood clotting factors ..."
 
Vol 11, No 4 (2015) INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Abstract  PDF (Eng)  similar documents
K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, D. A. Andreev, D. A. Sychev
"... of CYP3A4 isoenzyme activity and CYP2C19 polymorphisms on platelet aggregation. Material and methods ..."
 
Vol 15, No 3 (2019) Genetic, Epigenetic and Transcription Factors in Atrial Fibrillation Abstract  similar documents
O. V. Sapelnikov, A. A. Kulikov, O. O. Favorova, N. A. Matveeva, D. I. Cherkashin, O. A. Nikolaeva, R. S. Akchurin
"... potential links between single nucleotide polymorphisms and AF. The risk of AF in the general population ..."
 
Vol 9, No 6 (2013) APPLIED ASPECTS OF SLCO1B1 PHARMACOGENETIC TESTING FOR PREDICTING OF STATIN-INDUCED MYOPATHY AND PERSONALIZATION OF STATINS THERAPY Abstract  similar documents
D. A. Sychev, G. N. Shuev, A. B. Prokofiev
"... The clinical significance of the SLCO1B1 gene polymorphism (encoding an organic anion transport ..."
 
Vol 6, No 4 (2010) ACC/AHA CLOPIDOGREL CLINICAL ALERT. WHAT MUST BE MODERN ANTIPLATELET THERAPY? Abstract  similar documents
S. J. Martsevich
 
Vol 15, No 5 (2019) Association of rs556621 Polymorphism with Development of Stroke in Patients with Cardiovascular Pathology Abstract  similar documents
S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, S. V. Prokopenko, D. A. Nikulin, I. M. Platunova, S. S. Tretyakova, V. N. Maksimov, A. A. Gurazheva
"... Aim. To study the association of single nucleotide polymorphism rs556621 (G> T) with development ..."
 
Vol 3, No 2 (2007) VARFARIN DOSE REGIME APPROACHS BASED ON PHARMACOGENETICS TEST RESULTS: REAL POSSIBILITY TO OPTIMIZE THE PHARMACOTHERAPY Abstract  similar documents
D. A. Sychev, I. M. Antonov, S. V. Zagrebin, N. A. Gasanov, V. G. Kukes
"... of polymorphisms of genes of their biotransformation (CYP2C9) and molecule-targets (VKORC1). This created basis ..."
 
Vol 15, No 1 (2019) Personalized Medicine in the Treatment of Atrial Fibrillation: Myth or Reality? Abstract  similar documents
V. I. Podzolkov, A. I. Tarzimanova
"... and the study of different genes polymorphism predisposing to arrhythmia in general population. Gene ..."
 
Vol 10, No 3 (2014) THROMBOPHILIA AND INTENSITY OF THE INTRAVASCULAR MICROCOAGULATION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ATHEROTHROMBOSIS Abstract  similar documents
E. A. Shelest, A. E. Shuganov, L. I. Patrushev, I. N. Bokarev
"... thrombophilia gene polymorphisms than with one (p<0.01). Conclusion. The intensity of intravascular ..."
 
Vol 9, No 3 (2013) IMPACT OF LOCUS 9P21.3 SINGLE NUCLEOTIDE POLYMORPHISMS ON CORONARY ATHEROSCLEROSIS SEVERITY AND LONG-TERM OUTCOMES AFTER PERCUTANEOUS CORONARY INTERVENTION IN PATIENT WITH MYOCARDIAL INFARCTION Abstract  similar documents
P. A. Shesternya, G. V. Matyushin, S. Yu. Nikulina, A. S. Sergeeva
"... Aim. To investigate association between 9p21.3 locus single nucleotide polymorphisms (SNPs ..."
 
Vol 10, No 1 (2014) RARE CASES OF HYPERTROPHIC CARDIOMYOPATHY: VARIANTS AND CLINICAL OBSERVATIONS Abstract  similar documents
V. Yu. Zimina, G. V. Mislitskaya, S. A. Sayganov, S. D. Dzakhova
"... Hypertrophic cardiomyopathy belongs to a group of hereditary diseases due to sarcomere gene ..."
 
Vol 3, No 5 (2007) IDIOPATHIC SICK SINUS SYNDROME Abstract  similar documents
S. Y. Nikulina, V. A. Schulman, A. A. Chernova
 
Vol 13, No 4 (2017) GENETIC PREDICTORS OF INTENSIVE LIPID-LOWERING THERAPY EFFICACY AND ITS ANTI-INFLAMMATORY EFFECTS IN VERY HIGH CARDIOVASCULAR RISK PATIENTS Abstract  similar documents
M. A. Vorobyeva, M. M. Azova, O. O. Gigani, I. V. Garmash, S. V. Villevalde, Zh. D. Kobalava
"... , 62.1% of men) were included into the study. Polymorphism Phe189Ser of the CYP3A4 (gene encoding ..."
 
Vol 15, No 4 (2019) Pathogenic Variant Rs1471414348of the TTN Gene in the Patient with Familial Left Venticular Noncompaction Cardiomyopathy Abstract  similar documents
O. V. Kulikova, A. N. Meshkov, R. P. Myasnikov, A. V. Kiseleva, S. N. Koretsky, A. A. Zharikova, M. S. Kharlap, E. A. Mershina, V. E. Sinitsyn, O. P. Skirko, I. A. Efimova, M. S. Pokrovskaya, S. A. Boytsov, O. M. Drapkina
"... was diagnosed in the mother of proband. Later, was made exome sequencing in a group of genes related ..."
 
Vol 14, No 1 (2018) NEW APPROACHES TO INDIVIDUALIZED CHOICE OF ORAL ANTICOAGULANTS IN PATIENTS WITH ATRIAL FIBRILLATION Abstract  similar documents
Ju. P. Skirdenko, N. A. Nikolayev
"... , polymorphism of genes CYP2C9 and VKORC1 and the structure of food preferences. Results. Persons ..."
 
Vol 9, No 4 (2013) THE SIGNIFICANCE OF PHARMACOGENETIC CYP2C19 TESTING FOR PERSONALIZATION OF THE ANTIPLATELET THERAPY IN CARDIOLOGY PRACTICE Abstract  similar documents
K. B. Mirzaev, D. A. Sychev, D. A. Andreev, A. B. Prokofiev
"... The clinical significance  of CYP2C19 genetic polymorphism, associated with the violation ..."
 
Vol 10, No 5 (2014) DIFFERENTIAL DIAGNOSIS OF HEREDITARY SYNDROME OF HYPOCHOLESTEROLEMIA BY USING EXOMIC SEQUENCING Abstract  similar documents
A. I. Yershova, N. V. Shcherbakova, A. A. Suvorova, E. Y. Hlebus, I. V. Sidonets, A. N. Meshkov, S. A. Boytsov
"... to sequence the majority of regions of genome containing exons, protein-coding parts of genes. Heterozygous ..."
 
Vol 15, No 3 (2019) Modern Concepts of Fibromuscular Dysplasia of the Coronary Arteries Abstract  similar documents
E. L. Trisvetova
"... considers the participation of the PHACTR1 gene mutation and the transcriptional activity of the EDN1 gene ..."
 
Vol 11, No 1 (2015) MYOPATHY AS A SIDE EFFECT OF STATIN THERAPY: MECHANISMS OF DEVELOPMENT AND PROSPECTS FOR TREATMENT Abstract  similar documents
O. M. Drapkina, E. M. Chernova
"... of essential metabolites, destabilization of cell membranes, impaired expression of genes involved in apoptosis ..."
 
Vol 10, No 6 (2014) PHARMACOGENETIC TESTING OPPORTUNITIES IN CARDIOLOGY BASED ON EXOME SEQUENCING Abstract  similar documents
N. V. Shcherbakova, A. I. Ershova, A. A. Suvorova, E. Y. Hlebus, A. N. Meshkov, S. A. Boytsov
"... cardiac drugs and 7 genes which variants can influence cardiac drug metabolism were analyzed. According ..."
 
Vol 6, No 4 (2010) CORRELATIONS OF LOW MOLECULAR WEIGHT PHENOTYPE OF APOPROTEIN(A) AND SERUM LEVEL OF LIPOPROTEIN(A) WITH MULTIFOCAL ATHEROSCLEROSIS IN PATIENTS WITH CORONARY HEART DISEASE Abstract  similar documents
O. I. Afanasieva, M. V. Ezhov, M. I. Afanasieva, M. S. Safarova, J. V. Berestetskaya, S. N. Pokrovsky
"... (a) [apo(a)] polymorphism with the multifocal atherosclerosis in coronary heart disease (CHD ..."
 
Online First The Relationship of Endothelial Dysfunction with the Development of Diastolic Heart Failure in Patients with Hypertension Abstract  similar documents
T. V. Kalinkina, N. V. Lareva, M. V. Chistyakova, V. V. Gorbunov
"... and genotypes: 1 mutation nitric oxide synthase 3 gene NОS3 -786 T>C; (С-786Т) in relation to indicators of left ..."
 
Vol 15, No 4 (2019) Syndrome of Primary Myocardial Hypertrophy: Clinical and Morphological, Genetic Diagnostics and Comparison of Sarcomerial Variants of Cardiomyopathy and its Phenocopy Abstract  similar documents
O. V. Blagova, E. V. Zaklyazminskaya, E. A. Kogan, V. P. Sedov, G. М. Radzhabova, M. Е. Polyak, A. V. Nedostup
"... 3 and TNNT2 genes based on NGS technology (Ion Torrent PGMTM) with following Sanger resequencing ..."
 
Vol 14, No 1 (2018) NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME Abstract  similar documents
K. B. Mirzaev, O. D. Konova, E. A. Grishina, K. A. Ryzhikova, Zh. A. Sozaeva, D. A. Andreev, M. Y. Gilyarov, D. A. Sychev
"... polymorphisms in personalization of clopidogrel antiplatelet therapy. ..."
 
Vol 13, No 1 (2017) FROM PERSONALIZED TO PRECISION MEDICINE Abstract  similar documents
K. V. Raskina, E. Y. Martynova, A. V. Perfilyev, D. A. Sychev, G. N. Shuev, I. R. Fatkhutdinov, S. V. Musienko, D. A. Nikogosov, I. O. Zhegulina, L. G. Bavykina, Y. E. Poteshkin
"... characteristics into account: genes diversity, environment, lifestyles, and even bacterial microflora and also ..."
 
Vol 16, No 2 (2020) Algorithm for the Choice of Anticoagulant for Patients with Atrial Fibrillation Abstract  similar documents
Yu. P. Skirdenko, N. A. Nikolaev
"... of CYP2C9 and VKORC1 genes mutations were determined at the initial examination. These indicators were ..."
 
Vol 16, No 1 (2020) Cross-Sectional Study to Estimate the Prevalence of Familial Hypercholesterolemia in Selected Regions of the Russian Federation: Relevance, Design of the Study and Initial Characteristics of the Participants Abstract  similar documents
A. N. Meshkov, A. I. Ershova, S. A. Shalnova, A. S. Alieva, S. S. Bazhan, O. L. Barbarash, D. Y. Bogdanov, I. A. Viktorova, Yu. I. Grinshtein, D. V. Duplyakov, O. N. Kalachikova, A. V. Kontsevaya, R. A. Libis, I. V. Medvedeva, V. A. Nevzorova, N. N. Prishchepa, O. P. Rotar, V. N. Serebryakova, I. A. Trubacheva, T. M. Chernykh, E. A. Shutemova, O. M. Drapkina, S. A. Boytsov
"... arteries and heart and molecular genetic testing for LDLR, APOB and PCSK9 gene variants. Results. Out ..."
 
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