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AGE-DEPENDENT ASPECTS OF ACUTE CORONARY HEART DISEASE INCIDENCE RATE AND MORTALITY IN MEN AND WOMEN

https://doi.org/10.20996/1819-6446-2010-6-5-639-644

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Abstract

Aim. To study gender and age characteristics of incidence rate, mortality and lethality in acute coronary heart disease (ACHD).

Material and Methods. Analysis of the ACHD (ICD-10 codes: I21.0-I22.9, I20.0, I24) morbidity, mortality and lethality, depending on sex and age was performed in the population (n=285 736; 46% men) of several city administrative districts of Voronezh, Ryazan and Khanty-Mansiysk. Morbidity, mortality and lethality were calculated on the basis of medical documentation as well as cases identified by the study protocol.

Results. The ACHD morbidity and mortality in men were 1.99 and 1.79 times higher (p<0,001), respectively, than these in women. The studied parameters increase with age, reaching a maximum in 50-59 y.o., have a plateau in 60-79 y.o. and then they decrease. Morbidity and mortality in women increase with age, but reach a maximum in 70-79 y.o., being comparable with the male level, and then exceed it in ≥80 y.o. Age curve of lethality in men has J-alike shape with minimum in patients of 50-79 y.o. Women have a line age curve with minimum in patients of <50 y.o.

Conclusion. The population of ACHD patients should be considered according to both the sex and age: <50, 50-79 and ≥80 y.o. Every of these population group has special epidemiological characteristics.

About the Authors

S. A. Boytsov
Russian Cardiology Research and Production Complex
Russian Federation

researchers of RESONANCE (Russian multicenter epidemiologic study of acute coronary heart disease morbidity, mortality, diagnostic and treatment quality) study

Tretya Cherepkovskaya ul. 15a, Moscow, 121552

 



S. S. Yakushin
Ryazan State I.P. Pavlov Medical University
Russian Federation

researchers of RESONANCE (Russian multicenter epidemiologic study of acute coronary heart disease morbidity, mortality, diagnostic and treatment quality) study

Visokovoltnaya ul. 9, Ryazan, 390026 

 



N. N. Nikulina
Ryazan State I.P. Pavlov Medical University
Russian Federation

researchers of RESONANCE (Russian multicenter epidemiologic study of acute coronary heart disease morbidity, mortality, diagnostic and treatment quality) study

Visokovoltnaya ul. 9, Ryazan, 390026 

 



G. I. Furmenko
Voronezh N.N. Burdenko State Medical Academy
Russian Federation

researchers of RESONANCE (Russian multicenter epidemiologic study of acute coronary heart disease morbidity, mortality, diagnostic and treatment quality) study 

Studencheskaya ul. 10, Voronezh, 394036 



S. A. Akinina
Khanty-Mansiisk District Hospital
Russian Federation

researchers of RESONANCE (Russian multicenter epidemiologic study of acute coronary heart disease morbidity, mortality, diagnostic and treatment quality) study 

Kalinina ul. 40, Khanty-Mansiisk, Khanty-Mansiisk Autonomous District — Yugra, Tyumen Region, 628011 



References

1. Oganov R.G., Maslennikova G.Ia. Epidemiology and prevention of cardiovascular diseases in Russia. Cardiovascular disease: state of the problem. Proceedings of the 80th anniversary of acad. E.I. Chazov. M.: Media Medika; 2009. S.174-183. Russian (Оганов Р.Г., Масленникова Г.Я. Эпидемиология и профилактика сердечно-сосудистых заболеваний в России. Сердечно-сосудистая патология: современное состояние проблемы: сборник трудов к 80-летию акад. Е.И. Чазова. М.: Медиа Медика; 2009. С.174-183).

2. Kannel W.B. Some lessons in cardiovascular epidemiology from Framingham. Am J Cardiol 1976;37(2):269-282.

3. Metelitsa V.I., Mazur N.A. Epidemiology and prevention of coronary heart disease. M.: Meditsina; 1976. Russian (Метелица В.И., МазурН.А. Эпидемиология и профилактика ишемической болезни сердца. М.: Медицина; 1976).

4. Chazov E.I., Aronov D.M., Nikolaeva L.F. Peculiarities of the course of myocardial infarction as a function of age. Klin Med (Mosk) 1967;45(11):142-146. Russian (Чазов Е.И., Аронов Д.М., Николаева Л.Ф. Особенности течения инфаркта миокарда в зависимости от возраста. Клиническая медицина 1967;45(11):142-146).

5. Ovcharov V.K., Bystrova V.A. Mortality patterns and trends in circulatory diseases throughout the world. Sov Zdravookhr 1982;(5):33-9. Russian (Овчаров В.К., Быстрова В.А. Закономерности и тенденции смертности от болезней системыкровообращения в странах мира. Советское здравоохранение 1982;5:33-39).

6. The World Health Organization MONICA Project (monitoring trends and determinants in cardiovascular disease): a major international collaboration. WHO MONICA Project Princi￾pal Investigators. J Clin Epidemiol 1988;41(2):105-113.

7. Gafarov V.V., Gafarova F.V., Blaginina M.Yu. The WHO program "Registry of acute myocardial infarction: a 25-year epidemiological study of myocardial infarction in Russia (1977- 2001). Kardiologiya 1999;11:48-50. Russian (Гафаров В.В., Гафарова Ф.В., Благинина М.Ю. Программа ВОЗ «Регистр острого инфаркта миокарда»: 25-летнее эпидемиологическое исследование инфаркта миокарда в России (1977-2001). Кардио- логия 1999;11:48-50).

8. Kannel W.B., Abbott R.D. Incidence and prognosis of unrecognized myocardial infarction: an update on the Framingham study. N Engl J Med 1984;311(18):1144-1147.

9. Akhmeteli M.A. Epidemiological studies of cardiovascular diseases and their prevention. Sov Zdravookhr 1982;(5):20-4. Russian (Aхметели М.А. Эпидемиологические исследования сердечно-сосудистых заболеваний и их профилактика. Советское здравоохранение 1982;5:20-24).

10. Rissanen V., Romo M., Sarna S., Siltanen P. Deaths from ischemic heart disease in persons aged 65 or younger in Helsinki in 1970 with special reference to patho-anatomic findings in hearts. Acta Med Scand 1975;197(1-2):51-60.

11. Grabauskas V.I., Prokhorskas R.P., Baubinene A.V., Glazunov I.S. Risk of ischemic heart disease development in 45- to 59-year-old men. The results of a 5-year observation in the Kaunas population study. Kardiologiia 1980;20(3):68-72. Russian (Грабаускас В.И.,Прохорскас Р.П., Баубинене А.В., Глазунов И.С. Риск развития ишемической болезни сердца у 45-59-летних мужчин. Результаты 5-летнего наблюдения Каунасского популяционного исследования. Кардиология 1980;3:68-72).

12. Zhukovskiĭ G.S. Relation between various principalrisk factors and the incidence ofischemic heart disease in men 40-59 years of age. TerArkh 1981;53(1):33-40. Russian (Жуковский Г.С. Связь некоторых основных факторов риска с распространенностью ишемической болезни сердца у мужчин в возрасте 40-59 лет. Тер архив 1981;1:33-40).

13. The RISC Group. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. Lancet 1990;336(8719):827-830.

14. Low K.G., Joliceour M.R., Colman R.A. et al. Women participants in research: assessing progress. Women Health 1994;22(1):79-98.

15. Stone P.H., Thompson B., AndersonH.V. et al. Influence ofrace, sex, and age on management of unstable angina and non-Q-wave myocardial infarction: the TIMI III registry. JAMA 1996;275(14):1104-1112.

16. Alexander K.P., Roe M.T., Chen A.Y. et al. Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRU￾SADE National Quality Improvement Initiative.J Am Coll Cardiol 2005;46(8):1479-1487.

17. Alexander K.P., Newby L.K., Cannon C.P. et al. Acute coronary care in the Elderly, Part I. Non-ST-segment-elevation acute coronary syndromes. A scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology. Circulation 2007;115(19):2549-2569.

18. Alexander K.P., Newby L.K., Armstrong P.W. et al. Acute coronary care in the Elderly, Part II. ST-segment-elevation myocardial infarction. A scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology. Circulation 2007;115(19):2570-2589.

19. Harrington R.A. Women, acute ischemic heart disease, and antithrombotic therapy: challenges and opportunities. Circulation 2007;115(22):2796-2798.

20. Avezum A., Makdisse M., Spencer F. et al. Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2005;149(1):67-73.

21. International statistical classification of disease and related health problems. Tenth Revision. Volume 1 (Part 1). Geneva: WHO; 1992

22. International statistical classification of disease and related health problems. Tenth Revision. Volume 1 (Part 2). Geneva: WHO; 1992

23. Information and Methodical letter of Russian Ministry of Health dated 01.01.2002 "Use of the International Statistical Classification of Diseases and systems related to health, tenth revision (ICD-10) in the national medical practice".Russian (Информационно-методическое письмо Минздрава РФ от 01.01.2002 «Использование Международной статистической классификации болезней и систем, связанных со здоровьем, десятого пересмотра (МКБ-10) в практике отечественной медицины»).

24. Vlasov V.V. Epidemiology: a manual for high schools. 2nd ed. M.: GEOTAR-Med; 2006. Russian (Власов В.В. Эпидемиология: учебное пособие для ВУЗов. 2-е изд. М.: ГЭОТАР-Мед; 2006).


For citation:


Boytsov S.A., Yakushin S.S., Nikulina N.N., Furmenko G.I., Akinina S.A. AGE-DEPENDENT ASPECTS OF ACUTE CORONARY HEART DISEASE INCIDENCE RATE AND MORTALITY IN MEN AND WOMEN. Rational Pharmacotherapy in Cardiology. 2010;6(5):639-644. (In Russ.) https://doi.org/10.20996/1819-6446-2010-6-5-639-644

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