Preview

Rational Pharmacotherapy in Cardiology

Advanced search

PSYCHOMETRIC VISUAL ANALOGUE SCALE IN ASSESSMENT OF THE STABLE ANGINA SEVERITY AND EFFICACY OF ANTIANGINAL THERAPY

https://doi.org/10.20996/1819-6446-2011-7-5-80-82

Full Text:

Abstract

Aim. To evaluate possibilities of psychometric visual analog scales (VAS) for assessment of the stable angina severity and efficacy of antianginal therapy. Material and Methods. Patients (n=259), receiving different pharmaceutical forms of organic nitrates as antianginal therapy were included into the study. Patients (n=130) treated with retarded form of isosorbide mononitrate were enrolled into the first group. Patients (n=129) treated with isosorbide mononitrate in conventional form or isosorbide dinitrate in moderately long-acting form were enrolled into the second group. Questioning with the "Scales of the patient condition" and Seattle Angina Questionnaire was performed in all patients. Spearman's rank correlation coefficient and Fisher test was used to estimate the relationship of parameters determined with standard questionnaire and the quality of life (QL) level, assessed with VAS. Results. After 3 months the integral QL index increased from 3.5±0.2 to 7.4±0.25 points in the 1st group and from 3.3±0.2 to 6.1±0.22 in the 2nd group. The functional dependence of the integral QL index, determined with VAS, and angina pectoris functional class (FC) was found in the linear regression model for the Fisher test. Integral QL index in the range of 10.0-7.6 corresponds to angina pectoris FC I, 7.5-5.3 to FC II, and 5.2-3.9 to FC III. Integral QL index lower than 3.8 only hypothetically could correspond to angina pectoris FC IV. Conclusion. The VAS clinical  implementation is a simple and demonstrative method that adequately reflects the angina severity and the efficacy of antianginal treatment.

About the Author

E. V. Solyanik
Vladivostok State Medical University
Russian Federation


References

1. Simonenko V.B., Steklov V.I. A study of quality of life of cardiological patients. Klin Med (Mosk) 2007;85(3):11-5. Russian (Симоненко В.Б., Стеклов В.И. Исследование качества жизни у кардиологических больных. Клиническая медицина 2007; 3: 11-15).

2. Boden W.E., O’rourke R.A., Teo K.K. et al. COURAGE Trial Co-Principal Investigators and Study Coordinators The evolving pattern of symptomatic coronary artery disease in the United States and Canada: baseline characteristics of the Clinical Outcomes Utilizing Revascularizathion and Aggressive DruG Evaluathion (COURAGE). Am J Cardiol 2007; 99 (2): 208-12.

3. Boden W.E., O’rourke R.A., Teo K.K. et al. COURAGE Trial Research Group. Optimal medical therapy with or without PCI for stable coronary disease. N Engl Med 2007; 356: 1503-16.

4. Popov K.V., Kuimov A.D. Quality of life of patients with ischemic heart disease taking isosorbide-5-mononitrate in an outpatient setting. Kardiologiia 2003;43(7):53-4. Russian (Попов К.В., Куимов А.Д. Оценка качества жизни пациентов с ишемической болезнью сердца на фоне приема изо- сорбида-5-мононитрата в поликлинических условиях. Кардиология 2003; 7: 53-54).

5. Semenova Iu.E., Alimova E.V., Dmitrieva A. et al. Optimizing use of antianginal drugs: a randomized comparative study of isosorbide-5-mononitrate extended action in comparison with isosorbide dinitrate in patients with coronary heart disease with stable angina. Kardiovaskulyarnaya terapiya i profilaktika 2005; 4: 41-45. Russian (Семенова Ю.Э., Алимова Е.В., Дмитриева Н.А. и др. Оптимизация назначения антиангинальных препаратов: рандомизированное сравнительное изучение изосорбида-5-мононитрата продленного действия в сравнении с изосорбида динитратом у больных ишемической болезнью сердца со стабильной стенокардией напряжения. Кардиоваскулярная терапия и профилактика 2005; 4: 41-45).

6. Martsevich S.Iu., Semenova Iu.E., Alimova E.V. et al. Selection of therapy with nitrates in patients with stable effort angina: results of comparative study of common isosorbide dinitrate and long acting preparation of isosorbide-5-mononitrate. Kardiologiia 2005;45(11):42-5. Russian (Марцевич С.Ю., Семенова Ю.Э., Ю.Э., Алимова Е.В. и др. Выбор терапии нитратами у больных со стенокардией напряжения: сравнительное исследование обычных таблеток изосорбида динитрата и препарата изосорбида-5-мононитрата пролонгированного действия. Кардиология 2005; 11: 42-45).

7. Zateyshchikov D.A., Dankovtseva D.N. Place nitrates in modern cardiology. Kardiovaskulyarnaya terapiya i profilaktika. 2007; 6: 80-84. Russian (Затейщиков Д.А., Данковцева Д.Н. Место нитратов в современной кардиологии. Кардиоваскулярная терапия и профилактика. 2007; 6: 80-84).

8. Jansen R., Cleophas T.J., Zwinderman A. H. et al. Chronic nitrate therapy in patients with angina and comorbidity. Am J Ther 2006; 13(3): 188-91.

9. Kind P ., Lafata J.E., Matuszewski K. et al. The use of QALYs in clinical and patient decision – making: issues and prospects. Value and health 2009; 12: 27-30.

10. Yagudina R.I., Kulikov A.Yu., Litvinenko M.M. QAL Y: history , methodology and future methods. Farmakoekonomika 2010; 3(1): 11-14. Russian (Ягудина Р .И., Куликов А.Ю., Литвиненко М.М. QALY: история, методология и будущее метода. Фармакоэкономика 2010; 3(1): 11-14).

11. Belenkov Iu.N., Chazova I.E., Ratova L.G. et al. Results of international study of quality of life of patients with stable angina treated with nitrates (IQOLAN). Kardiologiia 2003;43(9):4-7. Russian (Беленков Ю.Н., Чазова И.Е., Ратова Л.Г . и др. Результаты международного исследования качества жизни пациентов со стабильной стенокардией на фоне терапии нитратами. Кардиология 2003; 9: 4-7).

12. Bullinger A. Translating health study questionnaires and evaluating health: the Quality of life a project approach. International of Quality of life assessment/ Clin Epidemiol 1998; 51: 913-23.

13. Karaeva E.V. Quality of life and compliance in patients with coronary heart disease in elderly with metabolic syndrome. Klinicheskaya gerontologiya 2006; 7: 56 -58. Russian (Караева Е.В. Качество жизни и комплаенс у больных ишемической болезнью сердца пожилого и старческого возраста с метаболическим синдромом. Клиническая геронтология 2006;7:56 -58).


For citation:


Solyanik E.V. PSYCHOMETRIC VISUAL ANALOGUE SCALE IN ASSESSMENT OF THE STABLE ANGINA SEVERITY AND EFFICACY OF ANTIANGINAL THERAPY. Rational Pharmacotherapy in Cardiology. 2011;7(5):591-595. (In Russ.) https://doi.org/10.20996/1819-6446-2011-7-5-80-82

Views: 441


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)