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ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION

https://doi.org/10.20996/1819-6446-2009-5-4-17-20

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Abstract

Aim. To evaluate efficacy of the combined therapy (sotalol and constant electric cardiostimulation in AAI regimen) at two atrial electrode position: in low back part of interatrial septum (IAS) and in right atrial auricle (RAA).

Material and methods. 20 patients with tachy-brady syndrome were examined. They were randomized in 2 groups depending on atrial electrode position. Sotalol (160 mg daily) was prescribed to all patients in a month after implantation of constant atrial pacemaker (CAP). A number of atrial fibrillation paroxysms (AFP) was evaluated initially, in a month after CAP implantation and in a month after start of sotalol therapy.

Results. Significant AFP reduction was observed in IAS stimulation, unlike RAA stimulation. Sotalol addition had essential significance in the termination or reduction of AFP. Sotalol effect did not depend on atrial electrode position.

Conclusion. Sotalol usage together with constant electric cardiostimulation significantly reduces AFP irrespectively of atrial electrode position. 

About the Author

T. N. Novikova
St-Petersburg Medical Academy of Postgraduate Studies, City Pokrovsky Hospital
Russian Federation

Chair of Cardiology named after M.S. Kushakovsky

City Antiarrhytmic Center

Kirochnaya ul. 41, St-Petersburg, 191015 Russia

Bolshoy pr. 85, Vasileostrovsky rayon, St-Petersburg, 199106



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For citation:


Novikova T.N. ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION. Rational Pharmacotherapy in Cardiology. 2009;5(4):17-20. (In Russ.) https://doi.org/10.20996/1819-6446-2009-5-4-17-20

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ISSN 1819-6446 (Print)
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