Rational Pharmacotherapy in Cardiology

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Evaluation of platelet function with subsequent modification of antiplatelet therapy regimen is one of the areas of personalized medicine. Analysis of the causes of inadequate antiplatelet action of clopidogrel, the association of residual platelet reactivity with clinical outcomes and a review of the research on the change of antiplatelet therapy in patients with ischemic heart disease after percutaneous interventions based on the results of platelet function testing, were the aim of this review.

About the Authors

K. B. Mirzaev
Russian Medical Academy of Postgraduate Education
Russian Federation
Barricadnaya ul. 2/1, Moscow, 123995 Russia

D. A. Andreev
I.M. Sechenov First Moscow State Medical University
Russian Federation
Trubetskaya ul. 8-2, Moscow, 119991 Russia

D. A. Sychev
Russian Medical Academy of Postgraduate Education
Russian Federation
Barricadnaya ul. 2/1, Moscow, 123995 Russia


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52. Conclusion interdisciplinary Expert Council of the Russian Society of Angiology and Vascular Surgery, Russian Scientific Society of endovascular diagnosis and treatment, the National Association for the fight against stroke, the National Scientific Society of inflammation. The role of testing platelet functional activity in the prevention of cardiovascular complications in patients receiving antiplatelet therapy. Ration Pharmacother Cardiol 2014; 10 (6): 679-87. Russian (Заключение междисциплинарного Совета Экспертов Российского общества ангиологов и сосудистых хирургов, Российского научного общества специалистов по рентгенэндоваскулярной диагностике и лечению, Национальной ассоциации по борьбе с инсультами, Национального научного общества воспаления. Роль тестирования функциональной активности тромбоцитов в профилактике сердечно-сосудистых осложнений у больных, получающих антитромбоцитарную терапию. Рациональная Фармакотерапия в Кардиологии 2014; 10(6): 679-87).


For citations:

Mirzaev K.B., Andreev D.A., Sychev D.A. EVALUATION OF PLATELET AGGREGATION IN CLINICAL PRACTICE. Rational Pharmacotherapy in Cardiology. 2015;11(1):85-91. (In Russ.)

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