Preview

Rational Pharmacotherapy in Cardiology

Advanced search

URAPIDIL IN THE TREATMENT OF MEDICAL EMERGENCIES CAUSED BY BLOOD PRESSURE INCREASE

https://doi.org/10.20996/1819-6446-2012-8-5-703-707

Full Text:

Abstract

Results of experimental and clinical studies devoted to urapidil combining central antihypertensive effect with peripheral vasodilatation are discussed. Scope of urapidil application is described; its good tolerability and safety are highlighted. Urapidil mode of application in different clinical situations accompanying by acute increase in blood pressure is specified.

About the Authors

N. I. Gaponova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation


V. R. Abdrakhmanov
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation


S. N. Tereschenko
Institute of Clinical Cardiology , Russian Cardiology Research and Production Center
Russian Federation


References

1. Gaponova N.I., Plavunov N.F., Tereshchenko S.N. et al. Clinico-statistical analysis of arterial hypertension complicated with hypertensive crisis in Moscow in 2005–2009. Kardiologiia 2011;51(2):40–

2. Russian (Гапонова Н.И., Плавунов Н. Ф., Бараташвили В. Л., и др. Клинико-статистический анализ артериальной гипертензии, осложненной гипертоническим кризом, в Москве за 2005–2009 гг. Кардиология 2011; (2): 40–44).

3. National guidelines for the diagnosis and treatment of hypertension (fourth revision). Sistemnye Gipertenzii 2010; (3): 5–26. Russian (Национальные рекомендации по диагностике и лечению артериальной гипертонии (четвертый пересмотр). Системные гипертензии 2010; (3): 5–26)..

4. Leonova M.V., Erofeeva S.B., Bykov A.V., Belousov Iu.B. Pharmacoeconomic analysis of antihypertensive therapy: advantages of fixed combinations. Kardiologiia 2008;48(1):43–50. Russian (Леонова М.В., Ерофеева С.Б., Быков А.В. Фармакоэкономический анализ антигипертензивной терапии: Преимущества фиксированных комбинаций. Кардиология 2008; (1): 43–50).

5. Yakhno N.N., Vilenskiy B.S. Stroke as a medical and social issue. Russkiy Meditsinskiy Zhurnal 2005; (12):807–15. Russian (Яхно Н.Н., Виленский Б.С. Инсульт как медико-социальная проблема. Русский Медицинский Журнал 2005; (12):807–15).

6. Putilina M.V., Soldatov A.M. Cerebral stroke in the elderly: clinical features, course and treatment. Mezhdunarodnyy Nevrologicheskiy Zhurnal 2006; (3): 11–17. Russian (Путилина М.В., Солдатов А.М. Церебральные инсульты в старческом возрасте: особенности клинической картины, течение, лечение. Международный Неврологический Журнал 2006; (3): 11–17).

7. Kolos I.P., Chazova I.E., Tereshchenko S.N., Nakonechnikov S.N. Risk of cardiovascular complications in patients with frequent hypertensive crises. Ter Arkh 2009;81(9):9–12. Russian (Колос И.П., Чазова И.Е., Терещенко С.Н. и др. Риск развития сердечно-сосудистых осложнений у пациентов с частыми гипертоническими кризами. Предварительные результаты многоцентрового ретроспективного исследования случай — контроль ОСАДА. Тер архив 2009; (9): 9–12).

8. European Stroke Organisation (ESO) Executive Committee and the ESO Writing Committee. Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008. Cerebrovasc Dis 2008; 25: 457–507.

9. Gillis R.A., Dretchen K.L., Namath I. et al. Hypotensive effect of urapidil: CNS site and relative contribution. J Cardiovasc Pharmacol 1987; 9: 103–109.

10. Tikhonoff V., Zhang H., Richart T. et al. Blood pressure as a prognostic factor after acute stroke. Lancet Neurol 2009; 8: 938–48.

11. Leira R., Millan M., Diez-Tejedor E. et al. Age Determines the Effects of Blood Pressure Lowering During the Acute Phase of Ischemic Stroke: The TICA Study. Hypertension 2009; 54: 769–74.

12. Prehn J.H., Welsch M., Backhauss C. et al. Effects of serotonergic drugs in experimental brain ischemia: evidence for a protective role of serotonin in cerebral ischemia. Brain Res 1993; 63: 10–20.

13. Semenova E.V., Golikov A.P., Ryabinin V.A., Luk'yanov M.M. Treatment of hypertensive crises in an integrated dynamic control. TOP Meditsina 1998; (2): 6–8. Russian (Семенова Е.В., Голиков А.П., Рябинин В.А., Лукьянов М.М. Лечение гипертонических кризов с использованием комплексного динамического контроля. ТОП Медицина 1998; (2): 6–8).

14. Arima H., Anderson C.S., Wang J.G. et al. Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial Investigators. Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage. Hypertension 2010; 56(5): 852–58.

15. Grossman E., Hironi A.N., Messerli F.H. Comparative tolerability profile of hypertensive crisis treatments. Drug Saf 1998; 19: 99–122.

16. Migneco A., Ojetti V., De Lorenzo A. et al. Hypertinsive crises: diagnosis and management in the emergency room. Eur Rev Med Pharmarcol Sciences 2004; 8: 143–52.

17. Morrell D.F. Qualitative controlled hypotension. Meditsina Neotlozhnykh Sostoyaniy 2007; (3): 127–

18. Russian (Morrell D.F. Качественная управляемая гипотензия. Медицина Неотложных Состояний 2007; (3): 127–34).

19. Hirschl M.M., Seidler D., Mullner M. et al. Efficacy of different antihypertensive drugs in the emergency department. Hypertens 1996; 24: 1684–89.

20. Hess W., Schulte-Sasse U., Tarnow J. et al. Comparison of phentolamine and urapidil in controlling acute intra-operative hypertension in patients subjected to coronary artery hypass surgery Eur J Anaesthesiol 1985; 2(1): 21–27.

21. Santiveri X., Ledesma M.: Urapidilo en anestesiologia Farmacologia e indicaciones. Rev Esp Anestesiologia 1988; 45: 189–97.

22. Yao D.K., Jia S.Q., Wang L., et al. Therapeutic effect of urapidil on myocardial perfusion in patients with ST-elevation acute coronary syndrome. Eur J Intern Med 2009; 20(2):152–57.

23. Alijotas-Reig J., Bove-Farre I., De Cabo-Frances F. et al. Effectiveness and safety of prehospital urapidil for hypertensive emergencies. Am J Emerg Med 2001; 19: 130–133.

24. Drobinski G., Montalescot G., Fossier J.M. et al. Haemodynamic еffects of intravenous urapidil in patients with advanced left ventricular failure. Drugs 1990; 40(4): 63–64.

25. Adnot S., Radermacher P., Andrivet P. et al. Effects of sodium nitroprusside and urapidill on gas exchange and ventilation: perfusion ratios in patients with congestive heart failure. Drugs 1990; 40 (4): 65–66.

26. Yamanishi T., Yasuda K., Homma Y. et al. A multicenter placebo-controled, double0blind trial of urapidil, an alpha-blocker, on neurogenic bladder dysfunction. Eur Urol 1999;35: 45–51.

27. Dolley M., Goa K.L.Urapidil. A reappraisal of its use in the management of hypertension. Drugs 1998; 56(5): 529–955.

28. Grishin O.V., Popov V.A., Farber M.A. et al. New features intensive antihypertensive therapy in the pre-hospital setting. Skoraya Meditsinskaya Pomoshch' 2011; (2): 9–14. Russian (Гришин О.В., Попов В.А., Фарбер М.А. и др. Новые возможности интенсивной антигипертензивной терапии на догоспитальном этапе. Скорая Медицинская Помощь 2011; (2): 9–14).

29. Trimarco B., Rosiello G., Feldhaus P. Efficacy of once-daily urapidil treatment in mild or moderate essential hypertension assessed by ambulatory 24-hour blood pressure monitoring. Drugs 1988; 35 Supll 6: 173–181.

30. Beller K.D., Boer R., Sanders K.H. et al. Blockade of α1-adrenoceptors favourable in hypotension induced by stimulation of serotonin1A receptors in conscious dogs? Drugs 1990; 40 (4): 38–41.


For citation:


Gaponova N.I., Abdrakhmanov V.R., Tereschenko S.N. URAPIDIL IN THE TREATMENT OF MEDICAL EMERGENCIES CAUSED BY BLOOD PRESSURE INCREASE. Rational Pharmacotherapy in Cardiology. 2012;8(5):703-707. (In Russ.) https://doi.org/10.20996/1819-6446-2012-8-5-703-707

Views: 1214


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)