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Early glucose metabolism disorders (GMD) are of interest in development of effective approaches to prevention of type 2 diabetes mellitus (DM). Data of international clinical trials shows that early GMD are an independent risk factor for cardiovascular disease. The possibilities of GMD prevention and early treatment are discussed. Antihyperglycemic medications classification, their mode of action and efficacy are presented from evidence-based medicine point of view. This data confirms that successful DM primary prevention at early stage of GMD reduces the risk of cardiovascular complications.

About the Authors

M. N. Mamedov
State Research Center for Preventive Medicine
Russian Federation

E. A. Poddubskaya
State Research Center for Preventive Medicine
Russian Federation

M. N. Kovrigina
State Research Center for Preventive Medicine
Russian Federation

Z. O. Ugurchieva
Ingush State University
Russian Federation

R. T. Digigova
Ingush State University
Russian Federation


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For citations:

Mamedov M.N., Poddubskaya E.A., Kovrigina M.N., Ugurchieva Z.O., Digigova R.T. PRIMARY PREVENTION OF DIABETES MELLITUS: CORRECTION OF EARLY DISORDERS OF GLUCOSE METABOLISM IN CARDIOLOGY PRACTICE. Rational Pharmacotherapy in Cardiology. 2012;8(1):81-87. (In Russ.)

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