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Rational Pharmacotherapy in Cardiology

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Hostility, Anger, Psycho-emotional Factors and Cardiovascular Disease

https://doi.org/10.20996/1819-6446-2022-04-09

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Abstract

The review presents the main aspects of the relationship between psychoemotional factors, hostility, anger and cardiovascular diseases. The first chapter describes the main historical stages in the study of this problem, starting from the Middle Ages and ending with fundamental research of the 19-20 centuries. In the second part, the authors demonstrated that hostility/anger are a risk factor for the CVD development and affect the prognosis and course of CVD (hypertension, ischemic heart disease, various cardiac arrhythmias, etc.). In the third chapter, there were studies that found that high rates of hostility/ anger reduced the effectiveness of cardiovascular therapy. In the fourth part, there are the main correlation mechanisms of negative emotions, hostility/anger and the cardiovascular system, carried out through the relationships with the activation of the hypothalamic-pituitary-adrenal, autonomic nervous system, platelet activation, with the changes in the risk factors characteristics etc. In the final chapter, the authors suggested prospects for further study of the problem, probably associated with the assessment of behavioral interventions, pharmacological or complex effects on the severity of hostility/anger to reduce CVD mortality in individuals with high rates of hostility / anger.

About the Authors

G. F. Andreeva
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Galiya F. Andreeva

Moscow



V. M. Gorbunov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Vladimir M. Gorbunov

Moscow



References

1. Willius FA, Keyes TE. Classics in cardiology. New York, NY: Dover; 1941.

2. Karlik LN. Claude Bernard (Klod Bernar). Moscow: Izdatel'stvo Nauka; 1964 (In Russ.) [Карлик Л.Н. Клод Бернар. М.: Издательство «Наука»; 1964].

3. Pokrovskij V. M., Korot'ko G. F. Human physiology (Fiziologiya cheloveka). 2003. Izdatel'stvo Medicina (Rus)

4. Ellsworth PC. William James and emotion: is a century of fame worth a century of misunderstanding? Psychol Rev. 1994;101(2):222-9. DOI:10.1037/0033-295x.101.2.222.

5. Cannon WB. The James-Lange theory of emotion: A critical examination and an alternative theory. Am J Psychol. 1987;100(3-4):567-86.

6. Pavlov I. P. Twenty years of experience in objective study of the higher activity (behavior) of animals. Moscow: Izdatelstvo Nauka; 1973 (In Russ.) [Павлов И.П. Двадцатилетний опыт объективного изучения высшей деятельности (поведения) животных. М.: Издательство Наука.; 1973].

7. Lang GF. Hypertensive disease. Moscow: Medgiz; 1950 (In Russ.) [Ланг Г. Ф. Гипертоническая болезнь. М.: Медгиз; 1950].

8. Dunbar HF. Emotions and Bodily Changes, Columbia University Press. Physical Therapy. 1935; 15(Issue 4):161. DOI:10.1093/ptj/15.4.161a.

9. Friedman M, Rosenman RH. Association of specific overt behavior pattern with blood and cardiovascular findings; blood cholesterol level, blood clotting time, incidence of arcus senilis, and clinical coronary artery disease. JAMA. 1959;1689(12):1286-96. DOI:10.1001/jama.1959.030002900 12005.

10. Haynes SG, Feinleib M, Kannel WB. The relationship of psychosocial factors to coronary heart disease in the Framingham Study. III. Eight-year incidence of coronary heart disease. Am J Epidemiol. 1980;111(1):37-58. DOI:10.1093/oxfordjournals.aje.a112873.

11. Dembroski TM, Costa PT Jr. Coronary prone behavior: components of the type A pattern and hostility. J Pers. 1987;55(2):211-35. DOI:10.1111/j.1467-6494.1987.tb00435.x.

12. Everson-Rose SA, Lewis TT. Psychosocial factors and cardiovascular diseases. Annu Rev Public Health. 2005;26:469-500. DOI:10.1146/annurev.publhealth.26.021304.144542.

13. Albus C. Psychological and social factors in coronary heart disease. Ann Med. 2010;42(7):487-94. DOI:10.3109/07853890.2010.515605.

14. Chida Y, Steptoe AJ. The association of anger and hostility with future coronary heart disease: a metaanalytic review of prospective evidence. Am Coll Cardiol. 2009;53(11):936-46. DOI:10.1016/j.jacc.2008.11.044.

15. Newman JD, Davidson KW, Shaffer JA, et al. Observed hostility and the risk of incident ischemic heart disease: a prospective population study from the 1995 Canadian Nova Scotia Health Survey. J Am Coll Cardiol. 2011;13;58(12):1222-8. DOI:10.1016/j.jacc.2011.04.044.

16. Davidson KW, Mostofsky E. Anger expression and risk of coronary heart disease: evidence from the Nova Scotia Health Survey. Am Heart J. 2010;159(2):199-206. DOI:10.1016/j.ahj.2009.11.007.

17. Compare A, Mommersteeg PM, Faletra F, et al. Personality traits, cardiac risk factors, and their association with presence and severity of coronary artery plaque in people with no history of cardiovascular disease. J Cardiovasc Med (Hagerstown). 2014;15(5):423-30. DOI:10.2459/JCM.0b013e328365cd8c.

18. Dembroski TM, MacDougall JM, Williams RB. Components of Type A, hostility, and anger-in: relationship to angiographic findings. Psychosom Med. 1985;47(3):219-33. DOI:10.1097/ 00006842-198505000-00001.

19. Wong JM, Sin NL, Whooley MA. A comparison of cook-medley hostility subscales and mortality in patients with coronary heart disease: data from the heart and soul study. Psychosom Med. 2014;76(4):311-7. DOI:10.1097/PSY.0000000000000059.

20. Angerer P, Siebert U, Kothny W. Impact of social support, cynical hostility and anger expression on progression of coronary atherosclerosis. J Am Coll Cardiol. 2000;36(6):1781-8. DOI:10.1016/ s0735-1097(00)00944-x.

21. Izawa S, Eto Y, Yamada KC, et al. Cynical hostility, anger expression style, and acute myocardial infarction in middle-aged Japanese men. Behav Med. 2011;37(3):81-6. DOI:10.1080/08964289.2011.585547.

22. Goodman M, Quigley J, Moran G, et al. Hostility predicts restenosis after percutaneous transluminal coronary angioplasty. Clin Proc. 1996;71(8):729-34. DOI:10.1016/S0025-6196(11)64836-2.

23. Keith F, Krantz DS, Chen R, et al. Anger, hostility, and hospitalizations in patients with heart failure. Health Psychol. 2017;36(9):829-838. DOI:10.1037/hea0000519.

24. Eaker ED, Sullivan LM, Kelly-Hayes M. Anger and hostility predict the development of atrial fibrillation in men in the Framingham Offspring Study. Circulation. 2004;109(10):1267-71. DOI:10.1161/01.CIR.0000118535.15205.8F.

25. Lampert R, Joska T, Burg M, et al. Emotional and physical precipitants of ventricular arrhythmia. Circulation. 2002;106(14):1800-5. DOI:10.1161/01.cir.0000031733.51374.c1.

26. Lampert R. Anger and ventricular arrhythmias. Curr Opin Cardiol. 2010;25(1):46-52. DOI:10.1097/HCO.0b013e32833358e8.

27. Peacock J, Whang W. Psychological distress and arrhythmia: risk prediction and potential modifiers. Prog Cardiovasc Dis. 2013;55(6):582-9. DOI:10.1016/j.pcad.2013.03.001.

28. Jamner LD, Shapiro D, Hui KK, et al. Hostility and differences between clinic, self-determined, and ambulatory blood pressure. Psychosom Med. 1993;55(2):203-11. DOI:10.1097/00006842199303000-00009.

29. Schneider RH, Egan BM, Johnson EH, et al. Anger and anxiety in borderline hypertension. Psychosom Med. 1986;48(3-4):242-8. DOI:10.1097/00006842-198603000-00009.

30. Jamner LD, Shapiro D, Goldstein IB, Hug R. Ambulatory blood pressure and heart rate in paramedics: effects of cynical hostility and defensiveness. Psychosom Med. 1991;53(4):393-406. DOI:10.1097/00006842-199107000-00005.

31. Pasic J, Shapiro D, Motivala S, Hui KK. Blood pressure morning surge and hostility. Am J Hypertens. 1998;11(2):245-50. DOI:10.1016/s0895-7061(97)00464-0.

32. Mezick EJ, Matthews KA, Hall M, et al. Low life purpose and high hostility are related to an attenuated decline in nocturnal blood pressure. Health Psychol. 2010;29(2):196-204. DOI:10.1037/a0017790.

33. Verberk WJ, Kroon AA, Thien T, et al. Prevalence of the white-coat effect at multiple visits before and during treatment. J Hypertens. 2006;24(12):2357-63. DOI:10.1097/01.hjh.0000251894.17132.54.

34. Schum JL, Jorgensen RS, Verhaeghen P, et al. Trait anger, anger expression, and ambulatory blood pressure: a meta-analytic review. J Behav Med. 2003;26(5):395-415. DOI:10.1023/a:102576-7900757.

35. Spicer J, Chamberlain K. Cynical hostility, anger, and resting blood pressure. J Psychosom Res. 1996;40(4):359-68. DOI:10.1016/0022-3999(95)00546-3.

36. Suls J, Wan CK, Costa PT Jr. Relationship of trait anger to resting blood pressure: a meta-analysis. Health Psychol. 1995;14(5):444-56. DOI:10.1037//0278-6133.14.5.444.

37. Casagrande M, Favieri F, Guarino A, et al. The Night Effect of Anger: Relationship with Nocturnal Blood Pressure Dipping. Int J Environ Res Public Health. 2020;17(8):2705. DOI: 10.3390/ijerph17082705.

38. Linden W, Klassen K, Phillips M. Can psychological factors account for a lack of nocturnal blood pressure dipping? Ann. Behav. Med. 2008;36:253–258. DOI:10.1007/s12160-008-9069-0.

39. Helmers KF, Baker B, O'Kelly B, Tobe S. Anger expression, gender, and ambulatory blood pressure in mild, unmedicated adults with hypertension. Ann Behav Med. 2000;22(1):60-4. DOI:10.1007/BF02895168.

40. Ohira T, Tanigawa T, Iso H, Sankai T, et al. Impact of anger expression on blood pressure levels in white-color workers with low-coping behavior. Environ Health Prev Med. 2000;5(1):37-42. DOI:10.1007/BF02935914.

41. Ohira T, Iso H, Tanigawa T, et al. The relation of anger expression with blood pressure levels and hypertension in rural and urban Japanese communities. J Hypertens. 2002;20(1):21-7. DOI:10.1097/00004872-200201000-00005.

42. Mills PJ, Dimsdale JE. Anger suppression: its relationship to beta-adrenergic receptor sensitivity and stress-induced changes in blood pressure. Psychol Med. 1993;23(3):673-8. DOI:10.1017/s0033291700025459.

43. Cox DE, DeVore BB, Harrison PK, Harrison DW. The effect of anger expression style on cardiovascular responses to lateralized cognitive stressors. Brain Inform. 2017;4(4):231-239. DOI:10.1007/s40708-017-0068-4.

44. Dorr N, Brosschot JF, Sollers JJ III, Thayer JF. Damned if you do, damned if you don't: the differential effect of expression and inhibition of anger on cardiovascular recovery in black and white males. Int J Psychophysiol. 2007;66(2):125-34. DOI:10.1016/j.ijpsycho.2007.03.022.

45. Treiber FA, Kamarck T, Schneiderman N, et al. Cardiovascular reactivity and development of preclinical and clinical disease states. Psychosom Med. 2003;65(1):46-62. DOI:10.1097/00006842200301000-00007.

46. Chida Y, Steptoe A. Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence. Hypertension. 2010;55(4):1026-32. DOI:10.1161/HYPERTENSIONAHA.109.146621.

47. Suarez EC, Williams RB. The relationships between dimensions of hostility and cardiovascular reactivity as a function of task characteristics. Jr. Psychosom Med. 1990;52(5):558-70. DOI:10.1097/00006842-199009000-00008.

48. Christensen AJ, Smith TW. Cynical hostility and cardiovascular reactivity during self-disclosure. Psychosom Med. 1993;55(2):193-202. DOI:10.1097/00006842-199303000-00008.

49. Tyra AT, Brindle RC, Hughes BM, Ginty AT. Cynical hostility relates to a lack of habituation of the cardiovascular response to repeated acute stress. Psychophysiology. 2020;57(12):e13681. DOI:10.1111/psyp.13681.

50. Carroll D, Davey Smith G, Sheffield D, Shipley MJ, Marmot MG. The relationship between socioeconomic status, hostility, and blood pressure reactions to mental stress in men: data from the Whitehall II study. Health Psychol. 1997;16(2):131-6. DOI:10.1037//0278-6133.16.2.131.

51. Suls J, Wan CK. The relationship between trait hostility and cardiovascular reactivity: a quantitative review and analysis. Psychophysiology. 1993;30(6):615-26. DOI:10.1111/j.1469-8986.1993. tb02087.x.

52. Bongard S, al'Absi M, Lovallo WR. Interactive effects of trait hostility and anger expression on cardiovascular reactivity in young men. Int J Psychophysiol. 1998;28(2):181-91. DOI:10.1016/s01678760(97)00095-0.

53. Miller SB, Dolgoy L, Friese M, Sita A. Dimensions of hostility and cardiovascular response to interpersonal stress. J Psychosom Res. 1996;41(1):81-95. DOI:10.1016/0022-3999(96)00090-6.

54. Smith TW, Allred KD. Blood-pressure responses during social interaction in high- and low-cynically hostile males. J Behav Med. 1989;12(2):135-43. DOI:10.1007/BF00846547.

55. Helmers KF, Krantz DS. Defensive hostility, gender and cardiovascular levels and responses to stress. Ann Behav Med. 1996;18(4):246-54. DOI:10.1007/BF02895286.

56. Vella EJ, Friedman BH. Autonomic characteristics of defensive hostility: reactivity and recovery to active and passive stressors. Int J Psychophysiol. 2007;66(2):95-101. DOI:10.1016/j.ijpsycho. 2007.03.014.

57. Helmers KF, Krantz DS, Merz CN, et al. Defensive hostility: relationship to multiple markers of cardiac ischemia in patients with coronary disease. Health Psychol. 1995;14(3):202-9. DOI:10.1037//0278-6133.14.3.202.

58. Jorgensen RS, Frankowski JJ, Lantinga LJ, et al. Defensive hostility and coronary heart disease: a preliminary investigation of male veterans. Psychosom Med. 2001;63(3):463-9. DOI:10.1097/00006842-200105000-00016.

59. Rodríguez C, Palmero Cantero F, Gómez-Íñiguez C. Blood pressure responses of defensive hostile women when facing a real stress task. Psychol Health. 2018;33(8):978-994. DOI: 10.1080/08870446.2018.1449952.

60. Kline KA, Fekete EM, Sears CM. Hostility, emotional expression, and hemodynamic responses to laboratory stressors: reactivity attenuating effects of a tendency to express emotion interpersonally. Int J Psychophysiol. 2008;68(3):177-85. DOI:10.1016/j.ijpsycho.2008.01.005.

61. Vella EJ, Friedman BH. Hostility and anger in: cardiovascular reactivity and recovery to mental arithmetic stress. Int J Psychophysiol. 2009;72(3):253-9. DOI:10.1016/j.ijpsycho.2009.01.003.

62. Chen YY, Gilligan S, Coups EJ, Contrada RJ. Hostility and perceived social support: interactive effects on cardiovascular reactivity to laboratory stressors. Ann Behav Med. 2005;29(1):37-43. DOI:10.1207/s15324796abm2901_6.

63. Holt-Lunstad J, Smith TW, Uchino BN. Can hostility interfere with the health benefits of giving and receiving social support? The impact of cynical hostility on cardiovascular reactivity during social support interactions among friends. Ann Behav Med. 2008;35(3):319-30. DOI:10.1007/s12160008-9041-z.

64. Lepore SJ. Cynicism, social support, and cardiovascular reactivity. Health Psychol. 1995;14(3): 210- 6. DOI:10.1037//0278-6133.14.3.210.

65. Gerin W, Pieper C, Levy R, Pickering T. G. Social support in social interaction: a moderator of cardiovascular reactivity. Psychosom Med. 1992;54(3):324-36. DOI:10.1097/00006842-19920500000008.

66. Kamarck TW, Manuck SB, Jennings JR. Social support reduces cardiovascular reactivity to psychological challenge: a laboratory model. Psychosom Med. 1990;52(1):42-58. DOI:10.1097/00006842199001000-00004.

67. Linden W, Chambers L, Maurice J, Lenz JW. Sex differences in social support, self-deception, hostility, and ambulatory cardiovascular activity. Health Psychol. 1993;12(5):376-80. DOI:10.1037//02786133.12.5.376.

68. Brownley KA, Light KC, Anderson NB. Social support and hostility interact to influence clinic, work, and home blood pressure in black and white men and women. Psychophysiology. 1996;33(4): 43445. DOI:10.1111/j.1469-8986.1996.tb01069.x.

69. Rutledge T, Linden W, Davies RF. Psychological risk factors may moderate pharmacological treatment effects among ischemic heart disease patients. Canadian Amlodipine/Atenolol in Silent Ischemia Study (CASIS) Investigators. Psychosom Med. 1999;61(6):834-41. DOI:10.1097/00006842199911000-00018.

70. Mann SJ, Gerber LM. Psychological characteristics and responses to antihypertensive drug therapy. Clin Hypertens (Greenwich). 2002;4(1):25-34. DOI:10.1111/j.1524-6175.2002.00493.x.

71. Pasic J, Shapiro D, Jamner LD, Hui KK. Hostility and the response to diuretic in mild-to-moderate hypertension. Am J Hypertens. 1994;7(6):503-8. DOI:10.1093/ajh/7.6.503.

72. Gerardi RJ, Blanchard EB, Andrasik F, McCoy GC. Psychological dimension of 'office hypertension'. Behav Res Ther. 1985;23(5):609-12. DOI:10.1016/0005-7967(85)90109-3.

73. Suls J. Anger and the heart: perspectives on cardiac risk, mechanisms and interventions. Prog Cardiovasc Dis. 2013;55(6):538-47. DOI:10.1016/j.pcad.2013.03.002.

74. Julkunen J, Salonen R, Kaplan G. A. et al. Hostility and the progression of carotid atherosclerosis. Psychosom Med. 1994;56(6):519-25. DOI:10.1097/00006842-199411000-00007.

75. Pajer KA. Cardiovascular disease risk factors in adolescents: do negative emotions and hypothalamic-pituitary-adrenal axis function play a role? Curr Opin Pediatr. 2007;19(5):559-64. DOI:10.1097/MOP.0b013e3282ef443a.

76. Korte SM, Koolhaas JM, Wingfield JC, McEwen BS. The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev. 2005;29(1):3-38. DOI:10.1016/j.neubiorev.2004.08.009.

77. May RW, Sanchez-Gonzalez MA, Hawkins KA, et al. Effect of anger and trait forgiveness on cardiovascular risk in young adult females. Am J Cardiol. 2014;114(1):47-52. DOI:10.1016/j.amjcard.2014.04.007.

78. León TC, Nouwen A, Sheffield D. Social support and individual variability in patterns of haemodynamic reactivity and recovery. Psychology and Health. 2007;22(4):473–492. DOI:10.1080/14768320600941806.

79. Starnino L, Dupuis G, Busque L, et al. The associations of hostility and defensiveness with telomere length are influenced by sex and health status. Biol Sex Differ. 2021;12(1):2. DOI:10.1186/s13293020-00349-w.

80. Brouilette S, Singh RK, Thompson JR, et al. White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol. 2003;23(5):842-6. DOI:10.1161/01.ATV. 0000067426.96344.32.

81. Haycock PC, Heydon EE, Kaptoge S, et al. Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis. BMJ. 2014;349:g4227. DOI:10.1136/bmj.g4227.

82. Bunde J, Suls J. A quantitative analysis of the relationship between the Cook-Medley Hostility Scale and traditional coronary artery disease risk factors. Health Psychol. 2006;25(4):493-500. DOI:10.1037/0278-6133.25.4.493.

83. Shen BJ, Countryman AJ, Spiro AIII, Niaura R. The prospective contribution of hostility characteristics to high fasting glucose levels: the moderating role of marital status. Diabetes Care. 2008;31(7):1293-8. DOI:10.2337/dc07-1945.

84. Vassou C, D'Cunha NM, Naumovski N, Panagiotakos DB. Hostile personality as a risk factor for hyperglycemia and obesity in adult populations: a systematic review. J Diabetes Metab Disord. 2020;19(2):1659-1669. DOI:10.1007/s40200-020-00551-y.

85. Progovac AM, Chang YF, Chang CH, et al. Are Optimism and Cynical Hostility Associated with Smoking Cessation in Older Women? Ann Behav Med. 2017;51(4):500-510. DOI:10.1007/s12160016-9873-x.

86. Thomas MC, Kamarck TW, Wright AGC, et al. Hostility Dimensions and Metabolic Syndrome in a Healthy, Midlife Sample. Int J Behav Med. 2020;27(4):475-480. DOI:10.1007/s12529-02009855-y.

87. Benotsch EG, Christensen AJ, McKelvey L. Hostility, social support, and ambulatory cardiovascular activity. J Behav Med. 1997;20(2):163-76. DOI:10.1023/a:1025530711432.

88. Kamarck TW, Haskett RF, Muldoon M, et al. Citalopram intervention for hostility: results of a randomized clinical trial. J Consult Clin Psychol. 2009;77(1):174-88. DOI:10.1037/a0014394.

89. Knutson B, Wolkowitz OM, Cole SW, et al. Selective alteration of personality and social behavior by serotonergic intervention. Am J Psychiatry. 1998;155(3):373-9. DOI:10.1176/ajp.155.3.37.

90. Gidron Y, Davidson K, Bata I. The short-term effects of a hostility-reduction intervention on male coronary heart disease patients. Health Psychol. 1999;18(4):416-20. DOI:10.1037//02786133.18.4.416.

91. Milani RV, Lavie CJ. Behavioral differences and effects of cardiac rehabilitation in diabetic patients following cardiac events. Am J Med. 1996;100(5):517-23. DOI:10.1016/s0002-9343(96)00020-4.


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Andreeva G.F., Gorbunov V.M. Hostility, Anger, Psycho-emotional Factors and Cardiovascular Disease. Rational Pharmacotherapy in Cardiology. 2022;18(2):191-199. (In Russ.) https://doi.org/10.20996/1819-6446-2022-04-09

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