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The “Inverse” Seasonal Blood Pressure Variability Phenotype

https://doi.org/10.20996/1819-6446-2021-06-13

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Abstract

The seasonal blood pressure variability (BPV) is known to demonstrate a typical winter peak. Recently, more attention is paid to the opposite situation: the summer BP levels being higher than those in winter. This phenomenon is called inverse BPV. The present article summarizes recent data on this topic. The data of the HOMED-BP project, as well as the results of the original prospective study in 770 hypertensive patients from two Russian Federation regions (mean follow-up duration 6.4 years), were used. According to the preliminary knowledge, the prevalence of inverse BPV in hypertensive patients is relatively high (15-25%). This phenomenon is more typical for treated patients, particularly for those on combination therapy, and is associated with beta-blocker intake. Higher duration of hypertension and higher levels of some risk factors (smoking) characterize the patients with inverse BPV. According to the HOMED-BP data, patients with inverse BPV had the highest overall cardiovascular risk (hazard ratio in comparison with the reference group of “minimal” “normal” BPV was 3.07; p=0.004). In summary, inverse BPV is a potentially unfavorable BP phenotype. However, its reproducibility and prospective value deserve further investigation. The absolute magnitude of seasonal BPV in these patients, calculated using different BP measurement methods, warrants special attention.

About the Authors

V. M. Gorbunov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Vladimir M. Gorbunov - eLibrary SPIN 5111-1303

Moscow



M. I. Smirnova
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Marina I. Smirnova

Moscow



Y. N. Koshelyaevskaya
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Yana N. Koshelyaevskaya - eLibrary SPIN 8660-0502

Moscow



N. N. Panueva
Ivanovo State Medical Academy
Russian Federation

Natalya N. Panueva - eLibrary SPIN 4098-3522



N. V. Furman
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

Nikolai V. Furman



P. V. Dolotovskaya
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

Polina V. Dolotovskaya - eLibrary SPIN 8240-2328



References

1. Van Rossum CT, Shipley MJ, Hemingway H, et al. Seasonal variation in case-specific mortality are there high risk groups& 25-year follow-up of civil servants from the first Whitehall study. Int J Epidemiol. 2001;30:1109-16. DOI:10.1093/ije/30.5.1109.

2. Schinkawa A, Ueda H, Hasuo Y et al. Seasonal variation of stroke incidence in Hisayama, Japan. Stroke 1990; 21^1262-1267. DOI:10.1161/01.STR.21.9.1262.

3. Wang Y, Levy CR, Attja J, et al. Seasonal variation in stroke in the Hunter region, Australia: a 5-year hospital-based study, 1995-2000. Stroke. 2003;34:1144-50. DOI:10.1161/01.STR.0000067703.71251.B6.

4. Keatinge WR, Coleshaw SR, Cotter F, et al. Increases in platelet and red cell counts, blood viscosity, and arterial pressure during mild surface cooling; factors in mortality from coronary and cerebral thrombosisin winter. Br Med J. 1984; 289:1405-8. DOI:10.1136/bmj.289.6456.1405.

5. Ockene IS, Chiriboga DE, Stanek EJ 3rd et al. Seasonal variation in serum cholesterol levels: treatment implication and possible mechanisms. Arch Intern Med. 2004;164:863-70. DOI:10.1001/archinte.164.8.863.

6. Sega R, Cesana G, Bombelli M, et al. Seasonal variations in home and ambulatory blood pressure in the PAMELA population. Pressione Arteriose Monitorate E Loro Associazioni. J Hypertens. 1998;16(11):1585–92.DOI:10.1097/00004872-199816110-00004.

7. Modesti PA, Morabito M, Bertolozzi I, et al. Weather-Related Changes in 24-Hour Blood Pressure Profile: Effects of Age and Implications for Hypertension Management. Hypertension. 2006;47(2):155-61. DOI:10.1161/01.HYP.0000199192.17126.d4.

8. Brennan PJ, Greenberg G, Miall WE, Thompson SG. Seasonal variation in arterial blood pressure. Br Med J. 1982:285:919-23. DOI:10.1136/bmj.285.6346.919.

9. Rose G. Seasonal variation in blood pressure in man. Nature. 1961;189:235.DOI:10.1038/189235a0.

10. Hanazawa T, Asayama K, Watabe D, et al. Association between amplitude of seasonal variation in self-measured home blood pressure and cardiovascular outcomes: HOMED-BP (Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure) Study. J Am Heart Assoc. 2018;7:1-14. DOI:10.1161/JAHA.117.008509.

11. Imai Y, Kario K, Shimada K, et al. The Japanese Society of Hypertension Guidelines for Self-monitoring of Blood Pressure at Home (Seconr Edition). Hypertension Res. 2012;35:777-95. DOI:10.1291/hypres.26.771.

12. Asayama K, Ohkubo T, Metoki H, et al. Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure. Hypertens Res. 2012;35:1102-10. DOI:10.1038/hr.2012.125.

13. Gorbunov VM, Smirnova MI, Koshelyaevskaya YaN, et al. Seasonal changes in blood pressure parameters in hypertensive patients intworegions of the Russian Federation: results of additional data analysis. Profilakticheskaya Meditsina. 2018;5:70-6 (In Russ) DOI:10.17116/profmed20182105170.

14. Gorbunov VM, Smirnova MI, Koshelyaevskaya YaN, et al. Seasonal blood pressure variability and its prognostic value in hypertensive patients (a prospective cohort study in two Russian Federation sites). Profilakticheskaya Meditsina. 2020;23(6):36-42 (In Russ) DOI:10.17116/profmed20202306136.

15. Minami J, Kawano Y, Yshimitsu T, et al. Seasonal variations in office, home and 24 h ambulatory blood pressure in patients with essential hypertension. J Hypertens. 1996;14:1421-5. DOI:10.1097/00004872-199612000-00006.

16. Nakajima J, Kawamura M, Fujiwara T, et al. Body height is a determinant of seasonal blood pressure variation in patients with essential hypertension. Hypertens Res. 2000;23:587-92. DOI:10.1291/hypres.23.587.

17. Aubiniere-Robb L, Jeemon P, Hastie CE, et al. Blood pressure response to patterns of weather fluctuations and effect on mortality. Hypertension. 2013;62:190-6. DOI:10.1161/HYPERTENSIONAHA.111.00686.

18. Ho PM, Magid DJ, Shetterly SM, et al. Importance of therapy intensification and medication nonadherence for blood pressure control in patients with coronary disease. Arch Intern Med. 2008;168:488-94. DOI:10.1001/archinternmed.2007.72.

19. Stergiou GS, Palatini P, Modesti PA, et al. Seasonal variation in blood pressure: Evidence consensus

20. and recommendations for clinical practice. Consensus statement by the European Society of Hypertension Working Group on Blood pressure Monitoring and Cardiovascular Variability. J Hypertens. 38:1235-43. DOI:10.1097/HJH.0000000000002341.

21. Gepts T, Nguen AM, Cleland C, et al. Accounting for blood pressure seasonability alters evaluation of practice-level blood pressure control intervention. Am J Hypertens. 2020;33:220-2. DOI:10.1093/ajh/hpz179.

22. Stergiou GS, Palatini P, Kollias A, et al. Seasonal blood pressure variation: a neglected confounder in clinical hypertension research and practice. Am J Hypertens. 2018;33(7):595-6. DOI:10.1093/ajh/hpaa056.

23. Kollias A, Kiryakoulis KG, Stamboliu E, et al. Seasonal blood pressure variation assessed by different measurement methods: systematic review and meta-analysis. J Hypertens. 2020;38(5):791-8. DOI:10.1097/HJH.0000000000002355.


For citation:


Gorbunov V.M., Smirnova M.I., Koshelyaevskaya Ya.N., Panueva N.N., Furman N.V., Dolotovskaya P.V. The “Inverse” Seasonal Blood Pressure Variability Phenotype. Rational Pharmacotherapy in Cardiology. 2021;17(3):470-475. (In Russ.) https://doi.org/10.20996/1819-6446-2021-06-13

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)