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Basic Aspects of Seasonal Cardiovascular Mortality

https://doi.org/10.20996/1819-6446-2021-02-01

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Abstract

The review demonstrates the main aspects of seasonal cardiovascular mortality. Climatic factors, including seasonal weather changes, have a significant impact on the biosphere. People are also characterized by the seasonal dynamics of the activity of many organs and systems, biochemical parameters, and mortality. Cardiovascular mortality is also characterized by seasonal fluctuations: in winter it is maximum, in summer it is minimal. The same patterns are characteristic of mortality from cardiovascular diseases (myocardial infarction, stroke, cardiac arrhythmias, etc.). The article presents the basic patterns of seasonal cardiovascular mortality in various climatic zones, the cardiovascular mortality of countries located in the equatorial and subequatorial climatic region. In addition, the mortality displacement phenomenon, the paradox of winter mortality. The main trends in changes in cardiovascular mortality over a long period of time are demonstrated. The paper discusses some of the mechanisms that underlie the dynamics of cardiovascular mortality during the year: seasonal fluctuations in the level of vitamin D, lipids in the blood plasma, changes in hemodynamic parameters, the effects of microbial and viral infections in the cold season, etc. In addition, data on seasonal the dynamics of risk factors for cardiovascular diseases is considered: an increase in body weight, a physical activity decrease, a change in the nutrition structure in the winter, the seasonal dynamics of depression, anxiety, hostility, the relationship of seasonal cardiovascular mortality with socio-economic, demographic and other factors. In conclusion, the main ways of development and prevention of seasonal CV cardiovascular mortality M, taking into account modern technologies at the international level, for state health departments, for specific patients, are demonstrated.

About the Authors

G. F. Andreeva
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Galiya F. Andreeva

Moscow

eLibrary SPIN: 5401-4631



V. M. Gorbunov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Vladimir M. Gorbunov

Moscow

eLibrary SPIN: 5111-1303



References

1. Fowler T., Southgate R.J., Waite T., et al. Excess Winter Deaths in Europe: A multi-country descriptive analysis. Eur J Public Health. 2015;25(2):339-45. DOI:10.1093/eurpub/cku073.

2. Boytsov S.A., Shalnova S.A., Deev A.D. The epidemiological situation as a factor determining the strategy for reducing mortality in the Russian Federation. Ter Arkhiv. 2020;92(1):4-9 (In Russ.) DOI:10.26442/00403660.2020.01.000510.

3. Research Organizing Committee of the ESSE-RF project. Epidemiology of cardiovascular diseases in different regions of Russia (ESSE-RF). The rationale for and design of the study. Profilakticheskaya Medicina. 2013;16(6):25-34 (In Russ.)

4. Boytsov S.A., Lukyanov M.M., Kontsevaya A.V., et al. Features of seasonal cardiovascular mortality in winter in russian regions with different climatic and geographical characteristics. Rational Pharmacotherapy in Cardiology. 2013;9(6):627-32 (In Russ.) DOI:10.20996/1819-6446-2013-9-6-627-632.

5. Sheth T., Nair C., Muller J., Yusuf S. Increased winter mortality from acute myocardial infarction and stroke: the effect of age. J Am Coll Cardiol. 1999;33(7):1916-9. DOI:10.1016/s0735-1097(99)00137-0.

6. Pan W.H., Li L.A., Tsai M.J. Temperature extremes and mortality from coronary heart disease and cerebral infarction in elderly Chinese. Lancet. 1995;345:353-5. DOI:10.1016/s0140-6736(95)90341-0.

7. Stewart S., McIntyre K., Capewell S., McMurray J.J.V. Heart failure in a cold climate: Seasonal variation in heart failure-related morbidity and mortality. J Am Coll Cardiol. 2002;39(5):760-6. DOI:10.1016/s0735-1097(02)01685-6.

8. Manfredini R., Portaluppi F., Salmi R., et al. Seasonal variation in the occurrence of nontraumatic rupture of thoracic aorta. Am J Emerg Med. 1999;17(7):672-4. DOI:10.1016/s0735-6757(99)90156-0.

9. Boulay F., Berthier F., Schoukroun G. Seasonal variations in hospital admission for deep vein thrombosis and pulmonary embolism: analysis of discharge data. BMJ. 2001;323(7313):601-2. DOI:10.1136/bmj.323.7313.601.

10. Bounameaux H., Hicklin L., Desmarais S. Seasonal variation in deep vein thrombosis. BMJ. 1996;312(7026):284-5. DOI:10.1136/bmj.312.7026.284.

11. Murphy N. F., Stewart S., MacIntyre K., et al. Seasonal variation in morbidity and mortality related to atrial fibrillation. Int J Cardiol. 2004; 97(2): 283-8. DOI:10.1016/j.ijcard.2004.03.041.

12. Page R.L., Zipes D.P., Powell J.L., et al. Seasonal variation of mortality in the Antiarrhythmics Versus Implantable Defibrillators (AVID) study registry. Heart Rhythm. 2004;1(4):435-40. DOI:10.1016/j.hrthm.2004.06.001.

13. Díaz A., Gerschcovich E.R., Díaz A.A. Seasonal Variation and Trends in Stroke Hospitalizations and Mortality in a South American Community Hospital. J Stroke Cerebrovasc Dis. 2013;22(7):e66-9. DOI:10.1016/j.jstrokecerebrovasdis.2012.04.007.

14. Alisov B.P., Poltaraus B.V. Klimatologiya. Climatology. Moscow: Izdatel'stvo Moskovskogo universiteta; 1974 (In Russ.)

15. Marti-Soler H., Gonseth S., Gubelmann P., et al. Seasonal variation of overall and cardiovascular mortality: A Study in 19 Countries from Different Geographic Locations. PLoS One. 2014;9(11):e113500. DOI:10.1371/journal.pone.0113500.

16. Egondi T., Kyobutungi C., Kovats S., et al. Time-series analysis of weather and mortality patterns in Nairobi’s informal settlements. Glob Health Action. 2012;5:23-32. DOI:10.3402/gha.v5i0.19065.

17. Miah A.H., Sutradhar S.R., Ahmed S., et al. Seasonal Variation in Types of Stroke and Its Common Risk Factors. Mymensingh Med J. 2012;21(1):13-20.

18. Hannan M. A., Rahman M.M., Haque A., et al. Stroke: Seasonal Variation and Association With Hypertension. Bangladesh Med Res Counc Bull. 2001;27(2):69-78.

19. Carson C., Hajat S., Armstrong B., Wilkinson P. Declining Vulnerability to Temperature-related Mortality in London over the 20th Century. Am J Epidemiol. 2006;164(1):77-84. DOI:10.1093/aje/kwj147.

20. Lerchl A. Changes in the seasonality of mortality in Germany from 1946 to 1995: the role of temperature. Int J Biometeorol. 1998;42(2):84-8. DOI:10.1007/s004840050089.

21. Saha M.V., Davis R.E., Hondula D.M. Mortality displacement as a function of heat event strength in 7 US cities. Am J Epidemiol. 2014;179(4):467-74. DOI:10.1093/aje/kwt264.

22. Gasparrini A., Armstrong B. Centre for Statistical Methodology. Time Series Regression Analysis [cited by Jan 20, 2020]. Available from: https://www.lshtm.ac.uk/research/centres/centre-statisticalmethodology/centre-themes.

23. Hajat S., Armstrong B.G., Gouveia N., et al. Mortality displacement of heat-related deaths: a comparison of Delhi, Sao Paulo, and London. Epidemiology. 2005;16(5):613-20. DOI:10.1097/01.ede.0000164559.41092.2a.

24. Rocklöv J., Forsberg B., Meister K. Winter mortality modifies the heat-mortality association the following summer. Eur Respir J. 2009;33:245-51. DOI:10.1183/09031936.00037808.

25. Stout R.W., Crawford V. Seasonal variations in fibrinogen concentrations among elderly people. Lancet. 1991;338:9-13. DOI:10.1016/0140-6736(91)90004-9.

26. Woodhouse P.R., Khaw K.T., Plummer M., et al. Seasonal variations of plasma fibrinogen and factor VII activity in the elderly: Winter infections and death from cardiovascular disease. Lancet. 1994;343:435-9. DOI:10.1016/s0140-6736(94)92689-1.

27. Keatinge W.R., Coleshaw S.R., Easton J.C., et al. Increased platelet and red cell counts, blood viscosity, and plasma cholesterol levels during heat stress, and mortality from coronary and cerebral thrombosis. Am J Med. 1986; 81(5):795-800. DOI:10.1016/0002-9343(86)90348-7.

28. Kingma B.R., Frijns A.J, Saris W.H., et al. Increased systolic blood pressure after mild cold and rewarming: relation to cold-induced thermogenesis and age. Acta Physiol (Oxf). 2011;203(4):419- 27. DOI:10.1111/j.1748-1716.2011.02336.x.

29. Zhu Z., Zhu S., Zhu J., et al. Endothelial dysfunction in cold-induced hypertensive rats. Am J Hypertens. 2002;15:176-80. DOI:10.1016/s0895-7061(01)02268-3.

30. Green D.J., Maiorana A.J., Siong J.H., et al. Impaired skin blood flow response to environmental heating in chronic heart failure. Eur Heart J. 2006;27:338-43. DOI:10.1093/eurheartj/ehi655.

31. Rowell L.B. Circulatory adjustments to dynamic exercise and heat stress: competing controls. In: Rowell L.B., ed. Human cardiovascular control. Oxford, U.K.: Oxford University Press; 1993: 363-406.

32. Balmain B.N., Jay O., Sabapathy S., et al. Altered thermoregulatory responses in heart failure patients exercising in the heat. Physiol Rep. 2016;4(21): pii:e13022. DOI:10.14814/phy2.13022.

33. Prodam, F., Zanetta S., Ricotti R. et al. Influence of ultraviolet radiation on the association between 25 hydroxy vitamin D levels and cardiovascular risk factors in obesity. J Pediatr. 2016;171:83-89.e1. DOI:10.1016/j.jpeds.2015.12.032.

34. Gouni-Berthold I., Krone W., Berthold H.K. Vitamin D and cardiovascular disease. Curr Vasc Pharmacol. 2009;7:414-22. DOI:10.2174/157016109788340686.

35. Papandreou, D. and Hamid, Z. T. The role of vitamin D in diabetes and cardiovascular disease: an updated review of the literature. Dis Markers. 2015;2015:580474. DOI:10.1155/2015/580474.

36. Alyami A.M., Lam V., Soares M.J., et al. The association of vitamin D statuswith dyslipidaemia and biomarkers of endothelial cell activation in older Australians. Nutrients. 2016;8(8):457. DOI:10.3390/nu8080457.

37. Nemerovski C.W., Dorsch M.P., Simpson R.U., et al. Vitamin D and Cardiovascular Disease. Pharmacotherapy. 2009;29:691-708. DOI:10.1592/phco.29.6.691.

38. Fyfe T., Dunnigan M.G., Hamilton E., Rae R.J. Seasonal variation in serum lipids, and incidence and mortality of ischaemic heart disease. J Atheroscler Res. 1968;8591-96. DOI:10.1016/s0368-1319(68)80112-7.

39. Gordon D.J., Hyde J., Trost D.C., et al. Cyclic seasonal variation in plasma lipid and lipoprotein levels: the Lipid Research Clinics Coronary Primary Prevention Trial Placebo Group. J Clin Epidemiol. 1988;41:679-89. DOI:10.1016/0895-4356(88)90120-5.

40. Donahoo W.T., Jensen D.R., Shepard T.Y., Eckel R.H. Seasonal variation in lipoprotein lipase and plasma lipids in physically active, normal eight humans. J Clin Endocrinol Metab. 2000;85:3065-8. DOI:10.1210/jcem.85.9.6816.

41. Ockene I.S., Chiriboga D.E., Stanek E.J. et al. Seasonal Variation in Serum Cholesterol Levels Treatment Implications and Possible Mechanisms. Arch Intern Med. 2004;164(8):863-70. DOI:10.1001/archinte.164.8.863.

42. Radke K.J., Izzo Jr J.L. Seasonal variation in haemodynamics and blood pressure-regulating hormones. J Hum Hypertens. 2010;24(6):410-6. DOI:10.1038/jhh.2009.75.

43. Kruse H.J., Wieczorek I., Hecker H., et al. Seasonal variation of endothelin-1, angiotensin II, and plasma catecholamines and their relation to outside temperature. J Lab Clin Med. 2002;140(4):236- 41. DOI:10.1067/mlc.2002.127169.

44. Smeeth L., Thomas S.L., Hall A.J., et. al. Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination. N Engl J Med. 2004;351:2611-8. DOI:10.1056/NEJMoa041747.

45. Ciszewski A., Bilinska Z.T., Brydak L.B., et al. Influenza vaccination in secondary prevention from coronary ischaemic events in coronary artery disease: FLUCAD study. Eur Heart J. 2008;29(11):1350- 8. DOI:10.1093/eurheartj/ehm581.

46. Boytsov S. A., M. Loukianov M. M., Platonova E. V. et al. Efficiency of Influenza Vaccination in Patients with Circulatory System Diseases under Dispensary Observation in Outpatient Clinics: Prospective Follow-up Monitoring Data. Rational Pharmacotherapy in Cardiology. 2016;12(6):703-10 (In Russ.) DOI:10.20996/1819-6446-2016-12-6-703-710.

47. Udell J.A., Zawi R., Bhatt D.L., et al. Association between influenza vaccination and cardiovascular outcomes in high-risk patients: a meta-analysis. JAMA. 2013;310(16):1711-20. DOI:10.1001/jama.2013.279206.

48. Youn J. C., Rim S. J., Park S., et al. Arterial stiffness is related to augmented seasonal variation of blood pressure in hypertensive patients. Blood Press. 2007;16(6):375-80. DOI:10.1080/08037050701642618.

49. Sega R., Cesana G., Bombelli M., et al. Seasonal variation in home ambulatory blood pressure in the PAMELA population. Pressione Arteriose Monitorate E Loro Associazioni. J Hypertens. 1998;16:1585-92. DOI:10.1097/00004872-199816110-00004.

50. Minami J., Kawano Y., Ishimitsu T., et al. Seasonal variations in office, home and 24 h ambulatory blood pressure in patients with essential hypertension. J Hypertens. 1996;14:1421-5. DOI:10.1097/00004872-199612000-00006.

51. Marti-Soler H., Gubelmann C., tefanie Aeschbacher S., еt al. Seasonality of Cardiovascular Risk Factors: An Analysis Including Over 230 000 Participants in 15 Countries. Heart. 2014;100(19):1517- 23. DOI:10.1136/heartjnl-2014-305623.

52. Visscher T.L.S., Seidell J.C. Time Trends (1993-1997) and Seasonal Variation in Body Mass Index and Waist Circumference in the Netherlands. Int J Obes Relat Metab Disord. 2004;28(10):1309- 16. DOI:10.1038/sj.ijo.0802761.

53. Ma Y., Olendzki B. C., Li W., et al. Seasonal Variation in Food Intake, Physical Activity, and Body Weight in a Predominantly Overweight Population. Eur J Clin Nutr. 2006;60(4):519-28. DOI:10.1038/sj.ejcn.1602346.

54. Matthews C.E., Freedson P.S., Hebert J.R., et al. Seasonal Variation in Household, Occupational, and Leisure Time Physical Activity: Longitudinal Analyses From the Seasonal Variation of Blood Cholesterol Study. Am J Epidemiol. 2001;153(2):172-83. DOI:10.1093/aje/153.2.172.

55. Toorn J.E., Cepeda M., Jong J.C.K., et al. Seasonal Variation of Diet Quality in a Large Middle-Aged and Elderly Dutch Population-Based Cohort. Eur J Nutr. 2020;59(2):493-504. DOI:10.1007/s00394-019-01918-5.

56. Marti-Soler H., Guessous I., Gaspoz J.M., et al. Seasonality of Nutrient Intake - An Analysis Including Over 44,000 Participants in 4 Countries. Clin Nutr ESPEN. 2017;21:66-71. DOI:10.1016/j.clnesp.2017.05.003.

57. Stelmach-Mardas M., Kleiser C., Uzhova I. Seasonality of food groups and total energy intake: a systematic review and meta-analysis. Eur J Clin Nutr. 2016;70(6):700-8. DOI:10.1038/ejcn.2015.224

58. Albus C. Psychological and social factors in coronary heart disease. Ann Med. 2010;42(7):487-94. DOI:10.3109/07853890.2010.515605.

59. Hare D. L., Toukhsati S. R., Johansson P., Jaarsma T. Depression and Cardiovascular Disease: A Clinical Review. Eur Heart J. 2014;35(21):1365-72. DOI:10.1093/eurheartj/eht462.

60. Harmatz M.G., Well A.D., Overtree C.E. Seasonal Variation of Depression and Other Moods: A Longitudinal Approach. J Biol Rhythms. 2000;15(4):344-50. DOI:10.1177/074873000129001350.

61. Winthorst W. H., Post W. J., Meesters Y., et al. Seasonality in Depressive and Anxiety Symptoms Among Primary Care Patients and in Patients With Depressive and Anxiety Disorders; Results From the Netherlands Study of Depression and Anxiety. BMC Psychiatry. 2011;11:198. DOI:10.1186/1471-244X-11-198.

62. Eagles J.M., McLeod I.H., Douglas A.S. Seasonal Changes in Psychological Well-Being in an Elderly Population. Br J Psychiatry. 1997;171:53-5. DOI:10.1192/bjp.171.1.53.

63. Mcmichael A.J., Wilkinson P., Kovats R.S., et al. International study of temperature, heat and urban mortality: The 'ISOTHURM' project. Int J Epidemiol. 2008;37(5):1121-31. DOI:10.1093/ije/dyn086.

64. Ballester F., Corella D., Pérez-Hoyos S., et al. Mortality as a function of temperature. A study in Valencia, Spain, 1991-1993. Int J Epidemiol. 1997;26(3):551-61. DOI:10.1093/ije/26.3.551.

65. D'ippoliti D., Michelozzi P., Marino C., et al. The impact of heat waves on mortality in 9 European cities: results from the EuroHEAT project. Environmental Health. 2010;9:37-45. DOI:10.1186/1476-069X-9-37.

66. Analitis A., Katsouyanni K., Biggeri A. Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project. Am. J. Epidemiol. 2008;168(12):1397-408. DOI:10.1093/aje/kwn266.

67. Chen K., Wolf K., Breitner S., et al. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas Kai Chena. Environ Int. 2018;116:186-96. DOI:10.1016/j.envint.2018.04.021.

68. Boĭtsov S.A., Kuznetsov A.S., Luk'ianov M.M., et al. The impact of abnormally high temperatures and ambient air pollution during summer months on mortality rates in the Moscow population and the possibilities of death prediction using linear regression analysis models. Profilakticheskaya Medicina. 2013;16(6);63-70 (In Russ.)

69. Eng H., Mercer J. B. The relationship between mortality caused by cardiovascular diseases and two climatic factors in densely populated areas in Norway and Ireland. J Cardiovasc Risk. 2000;7(5):369- 75. DOI:10.1177/204748730000700510.

70. Danet S., Richard F., Montaye M., et al. Unhealthy effects of atmospheric temperature and pressure on the occurrence of myocardial infarction and coronary deaths. A 10-year survey: the Lille-World Health Organization MONICA project (Monitoring trends and determinants in cardiovascular disease). Circulation. 1999;100(1):E1-7. DOI:10.1161/01.cir.100.1.e1.

71. The Eurowinter Group. Cold exposure and winter mortality from ischaemic heart disease, cerebrovascular disease, respiratory disease, and all causes in warm and cold regions of Europe. Lancet. 1997;349(9062):1341-6.

72. Zolotokrylin A.N., Titkova T.B., Bokuchava D.D. The Influence of Weather-Climatic and Social Factors on Population Mortality From Circulatory Diseases in Russia. Ter Arkhiv. 2018;90(3):53-9 (In Russ.) DOI:10.26442/terarkh201890353-59.

73. Achebak H., Devolder D., Ballester J. Trends in temperature-related age-specific and sex-specific mortality from cardiovascular diseases in Spain: a national time-series analysis. Lancet Planet Health. 2019;3:e297-306. DOI:10.1016/S2542-5196(19)30090-7.

74. Pan W.H., Li L.A., Tsai M.J. Temperature extremes and mortality from coronary heart disease and cerebral infarction in elderly Chinese. Lancet. 1995;345:353-5. DOI:10.1016/s0140-6736(95)90341-0.

75. Yin P., Chen R., Wang L., et al. The Added Effects of Heatwaves on Cause-Specific Mortality: A Nationwide Analysis in 272 Chinese Cities. Environ Int. 2018;121(Pt 1):898-905. DOI:10.1016/j.envint.2018.10.016.

76. Gemmell I., McLoone P., Boddy F., et al. Seasonal variation in mortality in Scotland Int. J. Epidemiol. 2000; 29 (2): 274-9. DOI:10.1093/ije/29.2.274.

77. Revich B.A. Heat waves as a risk factor for public health. Pulmonology. 2011; (4): 34-7 (In Russ.) DOI:10.18093/0869-0189-2011-0-4-34-37.

78. Heffernan C., Jones L., Ritchie B., et al. Local health and social care responses to implementing the national cold weather plan. Journal of Public Health. 2018;40(3):461-6. DOI:10.1093/pubmed/fdx120.

79. Masato G., Bone A., Charlton-Perez A., et al. Improving the Health Forecasting Alert System for Cold Weather and Heat-Waves In England: A Proof-of-Concept Using Temperature-Mortality Relationships. PLoS One. 2015; 10(10): e0137804. DOI:10.1371/journal.pone.0137804.


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Andreeva G.F., Gorbunov V.M. Basic Aspects of Seasonal Cardiovascular Mortality. Rational Pharmacotherapy in Cardiology. 2021;17(1):92-98. (In Russ.) https://doi.org/10.20996/1819-6446-2021-02-01

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