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Myocardial Infarction Complicated by Ischemic Stroke: Risk Factors, Prognosis, Unresolved Problems and Possible Methods of Prevention

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The present work is devoted to the analysis of modern publications on various aspects of the development and course of ischemic stroke in the presence of acute myocardial infarction. A literature search was conducted on the websites of cardiological and neurological societies, as well as on the PubMed, EMBASE, eLibrary databases using the keywords: myocardial infarction, acute coronary syndrome, stroke, acute cerebrovascular accident, myocardial infarction, acute coronary syndrome, stroke. The authors of this review found that although stroke is a relatively rare complication of myocardial infarction, its prevention is an extremely significant task, since it is associated with high mortality, disability and a significant increase in the cost of treatment. So, it is extremely important to detect thrombosis of the left ventricular cavity in a timely manner, to register preexisting atrial fibrillation that occurs earlier or for the first time, followed by the appointment of anticoagulant therapy. Timely reperfusion treatment, the use of statins and modern dual antithrombotic therapy can reduce the risk of developing cerebrovascular accident in patients with myocardial infarction. It is likely that a decrease in the activity of subclinical inflammation after myocardial infarction will also reduce the risk of stroke, as was recently shown in the COLCOT study. Currently, it remains relevant to search for new knowledge about the risk factors for stroke, which complicated the course of myocardial infarction, which will allow developing more effective and personalized preventive measures in a patient with acute coronary syndrome.

About the Authors

M. V. Zykov
Research Institute for Complex Issues of Cardiovascular Diseases; Sochi City Hospital №4
Russian Federation

Mikhail V. Zykov

Kemerovo, Sochi

eLibrary SPIN: 3357-1829

V. V. Butsev
Sochi City Hospital №4
Russian Federation

Vadim V. Butsev


eLibrary SPIN: 9729-632

R. R. Suleymanov
District Cardiology Dispensary, Center for Diagnosis and Cardiovascular Surgery
Russian Federation

Rafael R. Suleymanov



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Zykov M.V., Butsev V.V., Suleymanov R.R. Myocardial Infarction Complicated by Ischemic Stroke: Risk Factors, Prognosis, Unresolved Problems and Possible Methods of Prevention. Rational Pharmacotherapy in Cardiology. 2021;17(1):73-82. (In Russ.)

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