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SECONDARY PREVENTION OF STROKE IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION: THE CLINICIANS’ VIEWPOINT

https://doi.org/10.20996/1819-6446-2014-10-2-179-183

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Abstract

Atrial fibrillation is one of the main risk factor of ischemic stroke. Current problems of the management of patients with stroke due to non-valvular atrial fibrillation and secondary stroke prevention in these patients are considered. Data of own author’s observation for patients of this type during 6 months after discharge from the hospital are presented. The problems which patients faced with are analyzed. Comparative assessment of warfarin and dabigatran therapies is given.

About the Author

E. A. Drozdova
City Clinical Hospital № 13, Nizhny Novgorod
Russian Federation


References

1. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2009; 361(12):1139-51.

2. Heppell R. M., Berkin К. E., McLenachan J. M. et al. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in nonrheumatic atrial fibrillation. Heart 1997; 77: 407-11.

3. Psaty B.M., Manolio T.A., Kuller L.H. et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation 1997; 96: 2455-61.

4. Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994; 154: 1449-57.

5. Sherman DG, Kim SG, Boop BS, et al. Occurrence and Characteristics of Stroke Events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) Study. Arch Intern Med 2005;165:1185-91.

6. Krahn A. D., Manfreda J., Tate R. B. et al. The Natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba FollowUp Study. Am J Med 1995; 98: 476-84.

7. Wolf P. A., Abbott R. D., Kannel W. B. Atrial fibrillation as an independentrisk factorfor stroke: the Framingham Study. Stroke 1991; 22: 983-8.


For citation:


Drozdova E.A. SECONDARY PREVENTION OF STROKE IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION: THE CLINICIANS’ VIEWPOINT. Rational Pharmacotherapy in Cardiology. 2014;10(2):179-183. (In Russ.) https://doi.org/10.20996/1819-6446-2014-10-2-179-183

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)