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Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

https://doi.org/10.20996/1819-6446-2019-15-4-450-466

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Abstract

Participants of the study ESSE-RF-2 and co-authors: Moscow: Konstantinov V. V., Pokrovskaya M.S., Efimova I.A., Sivakova O.V.; Krasnodar: Alekseenko S.N., Gubarev S.V.; Оmsk: Livzan M.A., Grishechkina I.A., Rozhkova M.Yu.; Republic of Karelia: Vezikova N.N., Skopec I. S.; Ryazan: Filippov E.V., Dobrynina N.V., Nikulina N.N., Pereverzeva K.G., Moseychuk K.A.


Aim. Evaluate the prevalence, awareness, treatment, and control of hypertension among people aged 25-64 examined in 4 regions of the Russian Federation.

 Material and methods. Study materials were the representative selections of non-organized male (n=3000) and female (n=3714) inhabitants of aged 25-64 from 4 regions of the Russian Federation (Krasnodar region, Omsk region, Ryazan region, the Republic of Karelia), response rate>80%. Systematic stratified multilevel random election was formed with locality criteria (Kisch method). All the participants were interviewed using the standard questionnaire. The universal epidemiological methods and evaluation criteria were used. The study was approved by the local ethics Committee of National research center for preventive medicine. Participants signed informed consent. Hypertension was defined as an average systolic blood pressure (SBP)≥140 mmHg and/or average diastolic blood pressure (DBP)≥90 mmHg and/or antihypertensive therapy (AHT). The efficacy of treatment was the achievement of the target BP. Control group – patients with BP<140/90 mmHg.

 

Results. Mean SBP and DBP were 128.7±0,3 mmHg and 82.8±0.1 mmHg, respectively, higher BP was detected among male (p<0,001). The prevalence of hypertension was 44.2% that was higher among males than females (49.1% vs 39.9%, р˂0.0005), the highest hypertension frequency was in the Ryazan region. The awareness of hypertension was higher among females than in males 76.8% vs 69.4%. There were more persons with hypertension grade 1 among those, who were not aware of the hypertension. Medications were taken by 65.5% of females and 41.8% of males.

Angiotensin-converting enzyme inhibitors were received by 49.9% of patients, angiotensin II receptor antagonists by 30.9%, beta blockers – 29.5%, diuretics – 22.7%, calcium antagonists – 15.7%, centrally acting drugs – 3.3%, others – 0.2%. The lack of AHT intake was negatively associated with age, ischemic heart disease, urban life and hypo-HDL especially among males. Heart rate >80 per min in females increased by 1.7 times the probability of absence of AHT. The prevalence of effectively treated was 49.7% of the participants with hypertension. The associations between ineffective treatment and abdominal obesity, ischemic heart disease (males), age, rural type of settlement, obesity (females) were found. Only 24.9% of patients had control of the hypertension.

Conclusion. The prevalence of hypertension in Russian Federation remains high. An important task of the medical community is to identify the disease at an earlier stage of its development, before the appearance of complications. This approach can reduce the period from the onset of high blood pressure to a visit to the doctor.

About the Authors

Yu. A. Balanova
National Medical Research Center for Preventive Medicine
Russian Federation

Yulia A. Balanova MD, PhD, Leading Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



S. A. Shalnova
National Medical Research Center for Preventive Medicine
Russian Federation

Svetlana A. Shalnova – MD, PhD, Professor, Head of Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



A. E. Imaeva
National Medical Research Center for Preventive Medicine
Russian Federation

Asiia E. Imaeva – MD, PhD, Senior Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



А. V. Kapustina
National Medical Research Center for Preventive Medicine
Russian Federation

Anna V. Kapustina – MD, Senior Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



G. A. Muromtseva
National Medical Research Center for Preventive Medicine
Russian Federation

Galina A. Muromtseva – MD, PhD, Leading Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



S. V. Evstifeeva
National Medical Research Center for Preventive Medicine
Russian Federation

Svetlana E. Evstifeeva – MD, PhD, Senior Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



V. I. Tarasov
National Medical Research Center for Preventive Medicine
Russian Federation

Vladimir I. Tarasov – PhD (Physics and Mathematics), Senior Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases

Petroverigsky per. 10, Moscow, 101990 Russia



A. N. Redko
Kuban State Medical University
Russian Federation

Andrey N. Redko – MD, PhD, Professor, Head of Chair of Public Health, Health and Medical History

Mitrofana Sedina ul. 4, Krasnodar, 350063 Russia



I. A. Viktorova
Omsk State Medical University
Russian Federation

Inna A. Viktorova – MD, PhD, Professor, Head of Chair of Internal Medicine and Outpatient Therapy

Lenina ul. 12, Omsk, 644099 Russia



N. N. Prishchepa
Center for Medical Prevention of the Republic of Karelia
Russian Federation

Natalya N. Prishchepa ‒ MD, Head of Center for Medical Prevention of the Republic of Karelia

Kirov ul. 3, Petrozavodsk, 185000 Russia



S. S. Yakushin
Ryazan State Medical University named after Academician I.P. Pavlov
Russian Federation

Sergey S. Yakushin – MD, PhD, Professor, Head of Chair of Hospital Therapy

Visokovoltnaya ul. 9, Ryazan, 390026 Russia



S. A. Boytsov
National Medical Research Center of Cardiology
Russian Federation

Sergey A. Boytsov – MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences, Director 

Tretya Cherepkovskaya ul. 15a, Moscow, 121552 Russia



O. M. Drapkina
National Medical Research Center for Preventive Medicine
Russian Federation

Oxana M. Drapkina – MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences, Director

Petroverigsky per. 10, Moscow, 101990 Russia



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For citation:


Balanova Y.A., Shalnova S.A., Imaeva A.E., Kapustina А.V., Muromtseva G.A., Evstifeeva S.V., Tarasov V.I., Redko A.N., Viktorova I.A., Prishchepa N.N., Yakushin S.S., Boytsov S.A., Drapkina O.M. Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study). Rational Pharmacotherapy in Cardiology. 2019;15(4):450-466. (In Russ.) https://doi.org/10.20996/1819-6446-2019-15-4-450-466

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