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Differences in the Incidence of Major Risk Factors in Patients with Ischemic or Hemorrhagic Stroke in the Siberian Population

https://doi.org/10.20996/1819-6446-2018-14-4-509-514

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Abstract

Background. The study of the incidence of risk factors (RF) of stroke for primary and secondary prevention of this disease remains relevant. There are modifiable and non-modifiable RF.

Aim. To study the frequency of the main RF in patients with ischemic and hemorrhagic stroke in the urban population of Krasnoyarsk (Eastern Siberia).

Material and methods. Examination of 124 patients with an ischemic stroke and 28 with hemorrhagic was performed. Patients received treatment in neurologic center of Krasnoyarsk in 2014 year. The main criterion of inclusion was the confirmed diagnosis of an ischemic or hemorrhagic stroke. All patient had the clinic-tool and neurovisualizing examination and collecting the individual and family anamnesis with examination of modifiable and non-modifiable RF. The research of the neurologic status at patients both with ischemic, and with a hemorrhagic stroke was conducted by the standard technique. Based on results of computer or magnetic resonance imaging of a brain the diagnosis of an ischemic or hemorrhagic stroke was established.

Results. A distinctive feature of patients with hemorrhagic stroke was the occurrence of a vascular accident in younger age (6 years earlier) in comparison with ischemic stroke. Among patients with ischemic stroke elevated body mass index (BMI) was in 87 (70.2%) patients, burdened heredity was in 8.1% of cases, and 43.5% of patients were smokers. Among patients with hemorrhagic stroke 16 (57.1%) patients had elevated BMI. People with burdened heredity were not identified among them. Smoking was found in 22 (78.6%) patients in this group.

Conclusion. Improvement of treatment and prevention of an ischemic stroke are in many respects connected with clarification of RF and pathogenic mechanisms of its development. The rational pharmacotherapy directed to pointed impact on individual RF can reduce the risk of development of stroke not only at individual, but also at the population level.

About the Authors

S. Yu. Nikulina
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Svetlana Yu. Nikulina – MD, PhD, Professor, Vice-Rector for Academic Affairs, Head of Chair of Internal Medicine N1

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



A. A. Chernova
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation
Anna A. Chernova – MD, PhD, Associate Professor, Chair of Outpatient Therapy, Family Medicine and Healthy Lifestyle with a Course of Postgraduate Education, Head of Russian-Italian Laboratory of Medical Genetics, Research Institute of Molecular Medicine and Pathobiochemistry


D. A. Nikulin
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Dmitriy A. Nikulin – MD, PhD, Assistant, Chair of Neurology with Course of Rehabilitation of Postgraduate Education

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



V. A. Shulman
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Vladimir A. Shulman – MD, PhD, Professor, Chair of Internal Medicine N1

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



S. V. Prokopenko
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Semyon V. Prokopenko – MD, PhD, Head of Chair of Neurology with Course of Rehabilitation of Postgraduate Education 

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



I. M. Platunova
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Irina M. Platunova – MD, Post-Graduate Student, Chair of Internal Medicine N1 

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



O. V. Marilovceva
Krasnoyarsk Interdistrict Clinical Hospital №20 named after I. S. Berzon
Russian Federation

Olga V. Marilovceva – MD, PhD, Cardiologist

Instrumentalnaya ul. 12, Krasnoyarsk, 660123




I. I. Lebedeva
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Ilona I. Lebedeva – MD, Post-Graduate Student, Chair of Internal Medicine N1 

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



A. A. Semenchukov
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Aleksey A. Semenchukov  – Researcher, Russian-Italian Laboratory of Medical Genetics, Research Institute of Molecular Medicine and Pathobiochemistry; Senior Teacher, Chair of Biological Chemistry with Course of Medical, Pharmaceutical and Toxicological Chemistry

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



D. A. Yakovleva
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Dana A. Yakovleva – MD, Clinical Resident, Chair of Internal Medicine N1 

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



V. N. Maksimov
Research Institute of Therapy and Preventive Medicine
Russian Federation

Vladimir N. Maksimov – MD, PhD, Professor, Head of the Laboratory of Molecular Genetic Studies of Therapeutic Diseases

B. Bogatkova ul. 175/1, Novosibirsk, 630089




A. V. Kuskaeva
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Russian Federation

Alina V. Kuskaeva – MD, Post-Graduate Student, Chair of Internal Medicine N1 

Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022



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For citation:


Nikulina S.Y., Chernova A.A., Nikulin D.A., Shulman V.A., Prokopenko S.V., Platunova I.M., Marilovceva O.V., Lebedeva I.I., Semenchukov A.A., Yakovleva D.A., Maksimov V.N., Kuskaeva A.V. Differences in the Incidence of Major Risk Factors in Patients with Ischemic or Hemorrhagic Stroke in the Siberian Population. Rational Pharmacotherapy in Cardiology. 2018;14(4):509-514. (In Russ.) https://doi.org/10.20996/1819-6446-2018-14-4-509-514

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