Rational Pharmacotherapy in Cardiology

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A clinical role of biomarkers (especially, natriuretic peptides) is discussed in the article. The most important evidences of clinical effectiveness of using biomarkers in patients with suspected heart failure and in patients with confirmed diagnose of heart failure are reviewed. The need to use natriuretic peptides in patients with takotsubo syndrome is discussed. Limited diagnostic value of using natriuretic peptides in renal dysfunction, as well as in other diseases in which the concentration of natriuretic peptides may increase in the absence of heart failure, is also discussed.

About the Authors

S. R. Gilyarevskiy
Russian Medical Academy of Continuous Professional Education
Russian Federation

Sergey R. Gilyarevskiy – MD, PhD, Professor, Chair of Clinical Pharmacology and Therapy 

Barrikadnaya ul. 2/1, Moscow, 123995

M. V. Golshmid
Russian Medical Academy of Continuous Professional Education
Russian Federation

Maria V. Golshmid – MD, PhD, Associate Professor, Chair of Clinical Pharmacology and Therapy 

Barrikadnaya ul. 2/1, Moscow, 123995

I. M. Kuzmina
N.V. Sklifosovsky Research Institute of Emergency Care
Russian Federation

Irina M. Kuzmina – MD, PhD, Head of the Scientific Department of Emergency Cardiology 

Bolshaya Sukharevskaya pl. 3, Moscow, 129090


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