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ASSESSMENT OF CHANGES IN QUALITY OF PREHOSPITAL TREATMENT OF PATIENTS WITH ACUTE CORONARY SYNDROME IN THE LAST FEW YEARS: LIS-1 VS LIS-3 REGISTRIES

https://doi.org/10.20996/1819-6446-2017-13-6-827-834

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Abstract

Aim. To assess the changes in prehospital treatment of patients with acute coronary syndrome during the last years on the basis of the LIS-3 registry data.

Material and methods. Data of acute coronary syndrome hospital registry LIS-3 (2013-2015, n=397) and acute myocardial infarction hospital registry LIS-1 (2005-2007, n=1133) were used. To assess quality of prehospital treatment the fact of taking specific pharmacological groups of medications for primary and secondary cardiovascular diseases prevention was taken into consideration.

Results. Patients in the LIS-3 registry, in comparison with patients in the LIS-1 registry, more often took antiplatelet drugs (23.2% vs 15.7%, respectively; p<0.01) and statins (4.9% vs 2%, respectively; p<0.01). However, in general, the frequency of prescribing these groups of medications remained low. The use of medications of other pharmacological groups was comparable in patients of LIS-1 and LIS-3 registries (p>0.05). The quality of prehospital treatment did not differ significantly in survived and deceased patients of LIS-3 registry (p>0.05).

Conclusion. Only slight improvement in the quality of prehospital therapy in patients with acute coronary syndrome was revealed, mainly due to more frequent use of antiplatelet drugs and statins. It may be explained by poor detection of early forms of ischemic heart disease and underestimation of the importance of risk factors correction, both on the part of patients and on the part of physicians.

About the Authors

Yu. V. Semenova
National Research Center for Preventive Medicine
Russian Federation

Yulia V. Semenova – MD, Post-Graduate Student 

Petroverigskiy per. 10, Moscow, 10199



A. V. Zagrebelnyy
National Research Center for Preventive Medicine
Russian Federation

Alexander V. Zagrebelnyy – MD, PhD, Senior Researcher, Department of Preventive Pharmacotherapy 

Petroverigskiy per. 10, Moscow, 10199



N. P. Kutishenko
National Research Center for Preventive Medicine
Russian Federation

Natalia P. Kutishenko – MD, PhD, Professor, Head of Laboratory for Pharmacoepidemiological Studies, Department of Preventive Pharmacotherapy 

Petroverigskiy per. 10, Moscow, 10199



M. L. Ginzburg
Lyubertsy District Hospital №2
Russian Federation

Moisey L. Ginsburg – MD, PhD, Head of Cardiology Department 

Oktyabrskiy prospect. 338, Lyubertsy, Moscow Region, 140006



S. Yu. Martsevich
National Research Center for Preventive Medicine
Russian Federation

Sergey Yu. Martsevich – MD, PhD, Professor, Head of Department of Preventive Pharmacotherapy 

Petroverigskiy per. 10, Moscow, 10199

 

 



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For citation:


Semenova Y.V., Zagrebelnyy A.V., Kutishenko N.P., Ginzburg M.L., Martsevich S.Y. ASSESSMENT OF CHANGES IN QUALITY OF PREHOSPITAL TREATMENT OF PATIENTS WITH ACUTE CORONARY SYNDROME IN THE LAST FEW YEARS: LIS-1 VS LIS-3 REGISTRIES. Rational Pharmacotherapy in Cardiology. 2017;13(6):827-834. (In Russ.) https://doi.org/10.20996/1819-6446-2017-13-6-827-834

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