HEART RATE AND ITS ASSOCIATION WITH THE MAIN RISK FACTORS IN THE POPULATION OF MEN AND WOMEN OF WORKING AGE
Abstract
Aim. To study the association of heart rate (HR) with the health parameters obtained in the ESSE-RF study.
Material and methods. The data of the multicenter epidemiological study of ESSE-RF were used in the work. 8,343 men and 13,531 women aged 25-64 years were examined. The response to the survey was about 80%. The analysis is performed depending on the elevated heart rate. Education, place of residence, region, lipid profile, levels of C-reactive protein (CRP) and glucose, history of diabetes, anxiety and depression, elevated blood pressure were analyzed as factors possibly associated with increased heart rate. Epidemiological diagnosis of ischemic heart disease (IHD) was established using the Rose questionnaire, an electrocardiogram analysis, followed by the Minnesota code coding.
Results. Almost every fifth inhabitant had a pulse rate of more than 80 beats/min. No significant difference was found between the sexes. The increase in heart rate in men, starting in the age group 25-34 years to 45-54, and in women only up to 35-44 years with subsequent reduction in men and women was found. The prevalence of increased heart rate varies from region to region. The highest heart rate in men is recorded in Orenburg (33.1%), Ossetia (Alania) and Volgograd (29.7% and 27.6%, respectively), in women – in Vladivostok (37.4%), and the lowest heart rate in both gender groups
– in Samara (9.4% for men and 8.1% for women). Increase in heart rate in men with secondary education [odds ratio (OR) 1.24; 95% confidence interval (CI) 1.10-1.40], smokers and quitters (OR 1.90, 95% CI 1.63-2.27), who did not drink alcohol during the last year (OR 1.18, 95% CI 1.021.37), living in rural areas (OR 1.22, 95% CI 1.04-1.42), who are obese (OR 1.27, 95% CI, 1.101.45), having elevated blood pressure (OR 2.24, 95% CI 1.88-2.67), elevated levels of triglycerides, glucose and CRP was found after correction for age, region and all indicators included in the analysis (multidimensional model). The heart rate >80 beats/min was found significantly less often in people with history of myocardial infarction. A different model was found in women, it included, like in men, living in the village, elevated levels of blood pressure, triglycerides, glucose and CRP, but not education, smoking and alcohol consumption, obesity. Anxiety, low level of high-density lipoproteins and history of diabetes mellitus were also in the model in women.
Сonclusion. Significant associations between increased heart rate and metabolic risk factors, inflammation and residence in the village are found.
About the Authors
S. А. ShalnovRussian Federation
Svetlana A. Shalnova – MD, PhD, Professor, Head of Department of Epidemiology of Chronic Non-Сommunicable Diseases
. Petroverigsky per. 10, Moscow, 101990
A. D. Deev
Russian Federation
Alexander D. Deev – PhD (in Physics and Mathematics), Head of Laboratory of Biostatistics
Petroverigsky per. 10, Moscow, 101990
O. A. Belova
Russian Federation
Olga A. Belova – Deputy Chief Doctor
Sheremetevsky prospect 22, Ivanovo, 153012
Yu. I. Grinshtein
Russian Federation
Yury I. Grinshtein – MD, PhD, Professor, Head of Chair of Therapy, Institute of Postgraduate Education
Partizana Zheleznyaka ul. 1, Krasnoyarsk, 660022
D. V. Duplyakov
Russian Federation
Dmitry V. Duplyakov – MD, PhD, Professor, Deputy Chief Doctor
Aerodromnaya ul. 43, Samara, 123456
A. Yu. Efanov
Russian Federation
Alexey Yu. Efanov – MD, PhD, Assistant, Chair of Hospital Therapy
Odesskaya ul. 54, Tyumen, 625023
E. V. Indukaeva
Russian Federation
Elena V. Indukaeva – MD, PhD, Senior Researcher, Laboratory of Epidemiology of Cardiovascular Diseases
Sosnoviy bulvar 6, Kemerovo, 650002
N. V. Kulakova
Russian Federation
Natalia V. Kulakova – MD, PhD, Associate Professor, Chair of Therapy and Instrumental Diagnostics
Ostryakova prospect 2, Vladivostok, 690002
R. A. Libis
Russian Federation
Roman A. Libis – MD, PhD, Professor, Head of Chair of Hospital Therapy with Course of Clinical Pharmacology
Sovetskaya ul. 6, Orenburg, 123457
S. V. Nedogoda
Russian Federation
Sergey V. Nedogoda – MD, PhD, Professor, Head of Chair of Therapy and Endocrinology, Vice-Chancellor for Clinical Programs
Pavshikh Bortsov pl. 1, Volgograd, 400131
O. P. Rotar
Russian Federation
Oksana P. Rotar – MD, PhD, Head of Laboratory of Epidemiology of Hypertension
Akkuratova ul. 2, St. Petersburg, 197341
G. V. Tolparov
Russian Federation
Georgiy V. Tolparov – MD, Post-Graduate Student, Chair of Internal Medicine
Pushkinskaya ul. 40, Vladikavkaz, North Ossetia-Alania Republic, 362019
I. A. Trubacheva
Russian Federation
Irina A. Trubacheva – MD, PhD, Head of Department of Population Cardiology with Group of Scientific and Medical Information, Patenting and International Relations
Kievskaya ul. 111a, Tomsk, 634012
T. M. Chernykh
Russian Federation
Tatyana M. Chernykh – MD, PhD, Professor, Head of Chair of Hospital Therapy and Endocrinology
Studencheskaya ul. 10, Voronezh, 394005
A. A. Shabunova
Russian Federation
Alexandra A. Shabunova – PhD (in Economics), Professor, Deputy Director
Gorkogo ul. 56a, Vologda, 160014
S. A. Boytsov
Russian Federation
Sergey A. Boytsov – MD, PhD, Professor, Corresponding member of the Russian Academy of Sciences, Director
Tretya Cherepkovskaya ul. 15a, Moscow, 121552
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For citation:
Shalnov S.А., Deev A.D., Belova O.A., Grinshtein Y.I., Duplyakov D.V., Efanov A.Y., Indukaeva E.V., Kulakova N.V., Libis R.A., Nedogoda S.V., Rotar O.P., Tolparov G.V., Trubacheva I.A., Chernykh T.M., Shabunova A.A., Boytsov S.A. HEART RATE AND ITS ASSOCIATION WITH THE MAIN RISK FACTORS IN THE POPULATION OF MEN AND WOMEN OF WORKING AGE. Rational Pharmacotherapy in Cardiology. 2017;13(6):819-826. (In Russ.) https://doi.org/10.20996/1819-6446-2017-13-6-819-826