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Rational Pharmacotherapy in Cardiology

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ANGIOSARCOMA OF THE HEART – CLINICAL CASE

https://doi.org/10.20996/1819-6446-2017-13-3-339-345

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Abstract

Primary angiosarcoma of the heart, constituting 33% of primary heart malignancies in adults, refers to rare diseases with a difficult diagnosis. The article describes the case of primary angiosarcoma of the right atrium, diagnosed posthumously in a patient of 45 years old. The disease debuted in a previously healthy woman 45 years, 2 months before her death. There were episodes of sudden decrease in blood pressure with pain in the chest and short-term loss of consciousness, as well as moderate manifestations of heart failure (hydrothorax, small ascites, hydropericardium, hepatomegaly, leg shunting). The patient died suddenly, a pathologic study revealed an angiosarcoma of the right atrium with invasive growth, accompanied by inferior vena cava stenosis. Angiosarcoma of the heart should be included in a differential diagnosis of patient with pericardial effusion of unspecified genesis, syndromes of vena cava obstruction, unexplained right ventricular failure, syncope with a fall in blood pressure, especially in middle-aged patients.

About the Authors

N. Yu. Karpova
Pirogov Russian National Research Medical University
Russian Federation

Nina Yu. Karpova – MD, PhD, Professor, Nesterov Chair of Faculty Therapy 

Ostrovitianova ul. 1, Moscow, 117997



M. A. Rashid
Oncological Clinical Dispensary №1
Russian Federation

Mihail A. Rashid – MD, PhD, Therapist 

Baumanskaya ul. 17/1-3, Moscow, 105005



T. V. Kazakova
Pirogov Russian National Research Medical University
Russian Federation

Tatyana V. Kazakova – MD, PhD, Associate Professor, Nesterov Chair of Faculty Therapy 

Ostrovitianova ul. 1, Moscow, 117997



N. S. Chipigina
Pirogov Russian National Research Medical University
Russian Federation

Natalia S. Chipigina – MD, PhD, Associate Professor, Nesterov Chair of Faculty Therapy 

Ostrovitianova ul. 1, Moscow, 117997



A. V. Aksenova
Pirogov Russian National Research Medical University
Russian Federation

Angelina V. Aksenova – MD, PhD, Professor, Nesterov Chair of Faculty Therapy 

Ostrovitianova ul. 1, Moscow, 117997



R. V. Ershov
Oncological Clinical Dispensary №1
Russian Federation

Ruslan V. Ershov – MD, Resuscitator 

Baumanskaya ul. 17/1-3, Moscow, 105005



Zh. I. Banova
Oncological Clinical Dispensary №1
Russian Federation

Zhanna I. Banova – MD, Head of Department of Resuscitation 

Baumanskaya ul. 17/1-3, Moscow, 105005



E. M. Levin
Psychiatric Clinical Hospital № 1 named after N.A. Alexeev
Russian Federation

Eugenii M. Levin – MD, PhD, Head of Department of Pathological Anatomy 

Zagorodnoe shosse 2-1E, Moscow, 117152



A. A. Byshov
Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine
Russian Federation

Andrey A. Byshov – MD, Deputy Director for Clinical Expertise 

Zemlyanoy val ul. 53, Moscow



B. V. Uvarovskaya
City Clinical Hospital named after Brothers Bakhrushins
Russian Federation

Basana V. Uvarovskaya – MD, Head of Therapeutic Department of Day Hospital 

Stromynka ul. 7, Moscow, 107014



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For citation:


Karpova N.Y., Rashid M.A., Kazakova T.V., Chipigina N.S., Aksenova A.V., Ershov R.V., Banova Z.I., Levin E.M., Byshov A.A., Uvarovskaya B.V. ANGIOSARCOMA OF THE HEART – CLINICAL CASE. Rational Pharmacotherapy in Cardiology. 2017;13(3):339-345. (In Russ.) https://doi.org/10.20996/1819-6446-2017-13-3-339-345

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)