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THE STUDY "REGISTER OF PATIENTS AFTER ACUTE STROKE (REGION)." Part 1. Hospital Prospective Register of Patients after Acute Stroke (According to the Results of the Pilot Phase of the Study)

https://doi.org/10.20996/1819-6446-2016-12-6-645-653

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Abstract

Aim. To assess the main features of the clinical course of acute cerebrovascular accident (ACVA), its short-term and long-term outcomes and quality of pharmacotherapy based on hospital register.
Material and methods. The hospital register of acute stroke (AS) was organized in one of the cardiovascular centers in Moscow city. The results of the pilot part of the study are presented (170 patients hospitalized from January 01, 2014 to September 30, 2014 with ACVA living in the service area of one of the closest outpatient clinics). Presence of cardiovascular diseases (CVD) and their risk factors (RF), prehospital therapy, short-term complications including death and pharmacotherapy recommended to survived patients were analyzed using hospital medical records. During ambulatory follow-up (prospective part of the register) the vital status and pharmacotherapy were assessed.
Results. The majority of patients with AS had concomitant CVD (on average 2 per patient) and non CVD (on average 1.2 per patient). Data on the risk factors of CVD and their complications were reflected insufficiently in the medical records. Most patients in the prehospital period did not receive adequate treatment for the reduction in the cardiovascular risk. 90 patients survived and were discharged. 1.5-2 years after discharge, information on the vital status was available for 78 (86.7%) patients. 61 of them (78.2%) were alive and 17 (21.8%) died.
Conclusion. The pilot part of the REGION register revealed that the majority of patients with AS have concomitant CVD and non-CVD. The overall quality of pharmacotherapy, primary and secondary prevention of ACVA was far from that recommended in clinical guidelines, especially during follow-up in outpatient clinic.

About the Authors

S. A. Boytsov
State Research Centre for Preventive Medicine
Russian Federation

Sergey A. Boytsov – MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences, Director of State Research Center for Preventive Medicine

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S. Yu. Martsevich
State Research Centre for Preventive Medicine
Russian Federation

Sergey Yu. Martsevich – MD, PhD, Professor, Head of Department of Preventive Pharmacotherapy, State Research Centre for Preventive Medicine.

Petroverigsky per. 10, Moscow, 101990



N. P. Kutishenko
State Research Centre for Preventive Medicine
Russian Federation
Natalia P. Kutishenko – MD, PhD, Head of Laboratory for Pharmacoepidemiological Research, Department of Preventive Pharmacotherapy


M. M. Loukianov
State Research Centre for Preventive Medicine
Russian Federation
Michail M. Loukianov – MD, PhD, Leading Researcher, Department of Clinical Cardiology and Molecular Genetics


A. E. Mitichkin
Moscow City Clinical Hospital named after F.I. Inozemtsev (№36)
Russian Federation
Alexander E. Mitichkin – MD, PhD, Professor, Medical Director


R. V. Viskov
Moscow City Clinical Hospital named after F.I. Inozemtsev (№36)
Russian Federation
Roman V. Viskov – MD, PhD, Deputy Medical Director


L. V. Stakhovskaya
Pirogov Russian National Research Medical University
Russian Federation
Lyudmila V. Stakhovskaya – MD, PhD, Professor, Chair of Fundamental and Clinical Neurology and Neurosurgery


N. A. Shamalov
Pirogov Russian National Research Medical University
Russian Federation
Nikolay A. Shamalov – MD, PhD, Professor, Chair of Fundamental and Clinical Neurology and Neurosurgery


G. P. Arutyunov
Pirogov Russian National Research Medical University
Russian Federation
Grigory P. Arutyunov – MD, PhD, Professor, Chair of Propaedeutics of Internal Diseases, Physiotherapy and Radiology


I. V. Kokareva
Moscow City Outpatient Clinic №64
Russian Federation
 Inga V. Kokareva – MD, Medical Director


N. E. Parsadanyan
Moscow City Outpatient Clinic №64
Russian Federation
Natella E. Parsadanyan – MD, Deputy Medical Director


M. I. Chernyshova
Moscow City Outpatient Clinic №64
Russian Federation
Margarita I. Chernyshova – MD, Cardiologist


A. V. Zagrebelnyy
State Research Centre for Preventive Medicine
Russian Federation
Alexander V. Zagrebelnyy – MD, PhD, Senior Researcher, Department of Preventive Pharmacotherapy


N. A. Dmitrieva
State Research Centre for Preventive Medicine
Russian Federation
Nadezhda A. Dmitrieva – MD, PhD, Senior Researcher, Department of Preventive Pharmacotherapy


A. V. Akimova
State Research Centre for Preventive Medicine
Russian Federation
Anna V. Akimova – MD, Researcher, Department of Preventive Pharmacotherapy


G. I. Nikitina
Moscow City Clinical Hospital named after F.I. Inozemtsev (№36)
Russian Federation
Galina I. Nikitina – MD, Physician, Dedepartment of Anesthesiology and Intensive Care


O. V. Lerman
State Research Centre for Preventive Medicine
Russian Federation
Olga V. Lerman – MD, PhD, Senior Researcher, Department of Preventive Pharmacotherapy


V. P. Voronina
State Research Centre for Preventive Medicine
Russian Federation
Victoria P. Voronina – MD, PhD, Senior Researcher, Department of Preventive Pharmacotherapy


E. N. Belova
State Research Centre for Preventive Medicine
Russian Federation
Ekaterina N. Belova – Programmer, Laboratory of Biostatistics, Department of Epidemiology of Chronic Non-Communicable Diseases


E. N. Kudryashov
State Research Centre for Preventive Medicine
Russian Federation
Egor V. Kudryashov – Programmer, Laboratory of Biostatistics, Department of Epidemiology of Chronic Non-Communicable Diseases


A. D. Deev
State Research Centre for Preventive Medicine
Russian Federation
Alexander D. Deev – PhD (in Physics and Mathematics), Head of Laboratory of Biostatistics, Department of Epidemiology of Chronic Non-Communicable Diseases


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For citation:


Boytsov S.A., Martsevich S.Y., Kutishenko N.P., Loukianov M.M., Mitichkin A.E., Viskov R.V., Stakhovskaya L.V., Shamalov N.A., Arutyunov G.P., Kokareva I.V., Parsadanyan N.E., Chernyshova M.I., Zagrebelnyy A.V., Dmitrieva N.A., Akimova A.V., Nikitina G.I., Lerman O.V., Voronina V.P., Belova E.N., Kudryashov E.N., Deev A.D. THE STUDY "REGISTER OF PATIENTS AFTER ACUTE STROKE (REGION)." Part 1. Hospital Prospective Register of Patients after Acute Stroke (According to the Results of the Pilot Phase of the Study). Rational Pharmacotherapy in Cardiology. 2016;12(6):645-653. (In Russ.) https://doi.org/10.20996/1819-6446-2016-12-6-645-653

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)