Preview

Rational Pharmacotherapy in Cardiology

Advanced search

ESTIMATION OF RIGHT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE IN DIFFERENT AGE GROUPS

https://doi.org/10.20996/1819-6446-2016-12-3-277-284

Full Text:

Abstract

Aim. To study the parameters of diastolic function of the right ventricle (RV) in patients with ischemic heart disease (IHD) in different age groups. Material and methods. Patients (n=678) with IHD aged 38 to 85 years were included into the study. They underwent echocardiography with assessment of RV diastolic function. The following parameters were assessed: rate of early and late diastolic RV filling (Et and At), rate of early and late diastolic motion of the ring of the tricuspid valve (e't and a't), the propagation velocity of RV early filling flow (Vpt). All patients were divided into 2 groups: 1st one - patients up to 60 years old (n=282) and the 2nd group - patients 60 years and older (n=396). Results. In IHD patients RV diastolic dysfunction was detected more often in older age group (34.3%) than in group of patients younger than 60 years (22.3%, p=0.008). The next findings were found in the 2nd group: increase in At; reduction in Et/At ratio and e't/a't, as well as higher levels of systolic and mean pulmonary arterial pressure and the greater the thickness of the RV wall. The following parameters of diastolic RV function correlated with age: At (p=0.004); Et/At (p=0.001); Vpt (p=0.002) and e't/a't ratio (p=0.004). Conclusion. The results should be used in assessment of diastolic RV function in patients of different age groups.


About the Authors

R. A. Gajfulin
Research Institute of Complex Problems of Cardiovascular Diseases. Sosnovii bulvar 6, Kemerovo, 650002 Russia
Russian Federation


A. N. Sumin
Research Institute of Complex Problems of Cardiovascular Diseases. Sosnovii bulvar 6, Kemerovo, 650002 Russia
Russian Federation


O. G. Arhipov
Center of Rehabilitation “Topaz”. Leshoznaja ul. 1, Myski, 652840 Russia
Russian Federation


References

1. McDonald M.A., Ross H.J. Trying to succeed when the right ventricle fails. Curr Opin Cardiol 2009;24(3):239-45.

2. Frea S., Pidello S., Bovolo V. et al. Prognostic incremental role of right ventricular function in acute de-compensation of advanced chronic heart failure. Eur J Heart Fail 2016;16. [Epub ahead of print].

3. Aschauer S., Kammerlander A.A., Zotter-Tufaro C. et al. The right heart in heart failure with preserved ejection fraction: insights from cardiac magnetic resonance imaging and invasive haemodynamics. Eur J Heart Fail 2016;18(1):71-80.

4. Piccolo R., Niglio T., Spinelli L. et al. Reperfusion correlates and clinical outcomes of right ventricular dysfunction in patients with inferior ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention. Am J Cardiol 2014;114(2):243-9.

5. Di Bella G., Siciliano V., Aquaro GD. Et al. Right ventricular dysfunction: an independent and incremental predictor of cardiac deaths late after acute myocardial infarction. Int J Cardiovasc Imaging 2015;31(2):379-87.

6. Hutyra M., Skála T., Horák D. et al. Echocardiographic assessment of global longitudinal right ventricular function in patients with an acute inferior ST elevation myocardial infarction and proximal right coronary artery occlusion. Int J Cardiovasc Imaging 2015;31(3):497-507.

7. Kukulski T., She L., Racine N. et al. Surgical Treatment for Ischemic Heart Failure Investigators. Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction. J Thorac Cardiovasc Surg 2015;149(5):1312-21.

8. Pouleur A.M., Rousseau M.F., Ahn S.A. et al. Right Ventricular Systolic Dysfunction Assessed by Cardiac Magnetic Resonance Is a Strong Predictor of Cardiovascular Death After Coronary Bypass Grafting. Ann Thorac Surg 2016;22. [Epub ahead of print].

9. Chang W.T., Liu Y.W., Liu P.Y. et al. Association of Decreased Right Ventricular Strain with Worse Survival in Non-Acute Coronary Syndrome Angina. J Am Soc Echocardiogr. 2016 Apr;29(4):350-358.e4.

10. Axell R.G., Hoole S.P., Hampton-Till J., White P.A. RV diastolic dysfunction: time to re-evaluate its importance in heart failure. Heart Fail Rev 2015;20(3):363-73.

11. Murch S.D., La Gerche A., Roberts T.J. et al. Abnormal right ventricular relaxation in pulmonary hypertension. Pulm Circ. 2015;5(2):370-5.

12. Nartsissova G.P. The role of of the right ventricle in the pathology of cardiovascular system. Patologiya krovoobrashheniya i kardiokhirurgiya 2014;1:32-36. In Russian (Нарциссова Г.П. Роль правого желудочка в патологии сердечно-сосудистой системы. Патология кровообращения и кардиохирургия 2014; 1; 32-36).

13. Haddad F., Hunt S.A., Rosenthal D.N., Murphy D.J. Right ventricular function in cardiovascular disease, part I: Anatomy, physiology, aging, and functional assessment of the right ventricle. Circulation 2008;117(11):1436-48.

14. Kawut S.M., Lima J.A., Barr R.G. et al. Sex and race differences in right ventricular structure and function: the multi-ethnic study of atherosclerosis-right ventricle study. Circulation 2011;123(22):2542-51.

15. Armstrong D.W.J., Tsimiklis G., Matangi MF. Factors influencing the echocardiographic estimate of right ventricular systolic pressure in normal patients and clinically relevant ranges according to age. Can J Cardiol 2010;26(2):e35-e39.

16. Innelli P., Esposito R., Olibet M. et al. The impact of ageing on right ventricular longitudinal function in healthy subjects: a pulsed tissue Doppler study. Eur J Echocardiogr 2009;10:491-8.

17. Dalen H., Thorstensen A., Vatten L.J. et al. Reference values and distribution of conventional echocardiographic Doppler measures and longitudinal tissue Doppler velocities in a population free from cardiovascular disease. Circ Cardiovasc Imaging 2010;3(5):614-22.

18. Sumin А.N., Аrkhipov O.G. The right ventricle filling indices in different age groups. Serdechnaya Nedostatochnost' 2012;2:73-8. In Russian (Сумин А.Н., Архипов О.Г. Показатели наполнения правого желудочка в различных возрастных группах. Сердечная Недостаточность 2012; 2; 73-8).

19. Hoogslag G.E., Haeck M.L., Velders M.A. et al. Determinants of right ventricular remodeling following ST-segment elevation myocardial infarction. Am J Cardiol 2014;114(10):1490-6.

20. Schalla S., Jaarsma C., Bekkers S.C. et al. Right ventricular function in dilated cardiomyopathy and is-chemic heart disease: assessment with non-invasive imaging. Neth Heart J 2015;23(4):232-40.

21. Jin Y., Wang H., Wang Z. et al. The evaluation of preoperative right ventricular diastolic dysfunction on coronary artery disease patients with left ventricular dysfunction. Echocardiography 2014;31(10):1259-64.

22. Kuznetsov V.А., Yaroslavskaya E.I., Pushkarev G.S., Gorbatenko E.А. Factors associated with dilation of the right ventricle in patients with coronary artery disease with a history of macrofocal myocardial infarction. Patologiya Krovoobrashheniya i Kardiokhirurgiya 2014;1:37-41. In Russian (Кузнецов В.А., Ярославская Е.И., Пушкарев Г.С., Горбатенко Е.А. Факторы, ассоциированные с дилатацией правого желудочка у больных ишемической болезнью сердца с перенесенным крупноочаговым инфарктом миокарда. Патология кровообращения и кардиохирургия 2014; 1; 37-41).

23. Kuznetsov V.А., Yaroslavskaya E.I., Pushkarev G.S. et al. Dilatation of the right ventricle in patients with coronary heart disease without myocardial infarction (according to data of the "Register of coronary operations") Terapevticheskij Arkhiv 2015;9:34-8. In Russian (Кузнецов В.А., Ярославская Е.И., Пушкарев Г.С. и др. Дилатация правого желудочка у больных ишемической болезнью сердца без инфаркта миокарда (по данным «Регистра проведенных операций коронарографии»). Терапевтический архив 2015; 9; 34-8).

24. Sumin А.N., Аrkhipov O.G. Indicators of the right ventricle diastolic function with varying severity of pulmonary hypertension in patients with chronic pulmonary heart. Serdechnaya nedostatochnost' 2012;1:13-8. In Russian (Сумин А.Н., Архипов О.Г. Показатели диастолической функции правого желудочка при различной выраженности легочной гипертензии у больных хроническим легочным сердцем. Сердечная недостаточность 2012; 1; 13-8).

25. Fenster B.E., Holm K.E., Weinberger H.D. et al. Right ventricular diastolic function and exercise capacity in COPD. Respir Med 2015;109(10):1287-92.

26. Fredriksson A.G., Svalbring E., Eriksson J. et al. 4D flow MRI can detect subtle right ventricular dysfunction in primary left ventricular disease. J Magn Reson Imaging 2015.

27. Peyrou J., Parsaï C., Chauvel C. et al. Echocardiographic assessment of right ventricular systolic function in a population of unselected patients before cardiac surgery: a multiparametric approach is necessary. Arch Cardiovasc Dis 2014;107(10):529-39.

28. Fenster B.E., Browning J., Schroeder J.D. et al. Vorticity is a marker of right ventricular diastolic dysfunction. Am J Physiol Heart Circ Physiol 2015;309(6):H1087-93.

29. Pasipoularides A. Fluid dynamics of ventricular filling in heart failure: overlooked problems of RV/LV chamber dilatation. Hellenic J Cardiol 2015;56(1):85-95.


For citation:


Gajfulin R.A., Sumin A.N., Arhipov O.G. ESTIMATION OF RIGHT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE IN DIFFERENT AGE GROUPS. Rational Pharmacotherapy in Cardiology. 2016;12(3):277-284. https://doi.org/10.20996/1819-6446-2016-12-3-277-284

Views: 438


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)