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COMPARATIVE EFFICACY AND SAFETY OF NEW ORAL ANTICOAGULANTS

https://doi.org/10.20996/1819-6446-2013-9-4-433-438

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Abstract

Indirect comparisons of new oral anticoagulants are performed with focus on their safety. Apixaban, an oral inhibitor of Xa factor, nowadays can be considered as a drug with very good safety profile according to randomized trials results and performed indirect comparisons.

About the Authors

V. A. Sulimov
I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation


D. A. Napalkov
I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation


A. A. Sokolova
I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation


References

1. Camm AG, Lip GYH, De Caterina R, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation. Eur Heart J 2012; 33: 2719–47.

2. Sulimov VA, Golitsyn SP, Panchenko, EP, et al. Diagnosis and treatment of atrial fibrillation, 2012. RCS, RSSA and ACVS Recommendations. Issue 2. Available at: http://scardio.ru/content/Guidelines/Rekomen- dations_fibrillyacia_predserdii_2012.pdf. Date of access: 28.06.2013. Russian (Сулимов В.А., Голицын С.П., Панченко Е.П., и др. Диагностика и лечение фибрилляции предсердий 2012. Рекомендации РКО, ВНОА и АССХ. Выпуск 2. Доступно на: http://scardio.ru/content/Guide- lines/Rekomendations_fibrillyacia_predserdii_2012.pdf. Дата доступа: 28.06.2013).

3. Connolly SJ, Connolly SJ, Ezekowitz MD, et al., for the RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361: 1139–51.

4. Patel MR, Mahaffey KW, Garg J, et al., for the ROCKET-AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011; 365: 883–91.

5. Granger CB, Alexander JH, McMurray JJ, et al., for the ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2011; 365: 981–92.

6. Lip GYH, Larsen TB, Skjoth F, Rasmussen LH. Indirect comparisons of new oral anticoagulant drugs for efficacy and safety when used for stroke prevention in atrial fibrillation. J Am Coll Cardiol 2012; 60 (8): 738–46.

7. Schneeweiss S, Gagne JJ, Patrick AR, Choudkhry NK, Avorn J. Comparative efficacy and safety of new oral anticoagulants in patients with atrial fibrillation. Cardiovasc Qual Outcomes 2012; 5 (4): 480–86.


For citation:


Sulimov V.A., Napalkov D.A., Sokolova A.A. COMPARATIVE EFFICACY AND SAFETY OF NEW ORAL ANTICOAGULANTS. Rational Pharmacotherapy in Cardiology. 2013;9(4):433-438. (In Russ.) https://doi.org/10.20996/1819-6446-2013-9-4-433-438

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)