Rational Pharmacotherapy in Cardiology

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Optimization of the pharmacotherapy in preoperative period is the cornerstone of the concept of risk modification of cardiovascular complications in the perioperative period. Therefore, special attention has recently been focused on the use of beta-blockers in the postoperative period. Nowadays convincing evidence base for the use of this class of drugs in the perioperative period that was the basis for the development of clinical guidelines is accumulated. Moreover, results of large randomized trials of beta-blockers are controversial. This has resulted in significant differences in the classes of recommendations and levels of evidence.
Analysis of the results of basic researches and the provisions of recommendations of the international and national professional medical societies on the use of beta-blockers in patients with cardiovascular disease to reduce the risk of cardiac complications in the perioperative period for planned extracardiac surgical procedures is presented.

About the Authors

V. V. Samoylenko
Russian National Research Medical University named after N.I. Pirogov, Moscow
Russian Federation

O. P. Shevchenko
Russian National Research Medical University named after N.I. Pirogov, Moscow
Russian Federation

V. I. Burtsev
I.M. Setchenov First Moscow State Medical University, Moscow
Russian Federation


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For citation:

Samoylenko V.V., Shevchenko O.P., Burtsev V.I. USE OF BETA-BLOCKERS IN THE PERIOPERATIVE PERIOD: HOW STRONG ARE THE EVIDENCES? Rational Pharmacotherapy in Cardiology. 2013;9(4):420-426. (In Russ.)

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ISSN 1819-6446 (Print)
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