Rational Pharmacotherapy in Cardiology

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Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation. List of drugs that cause QT prolongation is constantly growing and being updated. The review contains current data on the clinical significance of the control of QT interval duration within drug therapy. Clinical conditions associated with an increased risk of QT interval prolongation are described. Drugs that can induce QT prolongation are also discussed.

About the Authors

N. V. Furman
Saratov Research Institute of Cardiology, Saratov
Russian Federation

S. S. Shmatova
Saratov Research Institute of Cardiology, Saratov
Russian Federation


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For citations:

Furman N.V., Shmatova S.S. CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION. Rational Pharmacotherapy in Cardiology. 2013;9(3):311-315. (In Russ.)

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